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Anti-Phospho-ACK1 (Tyr284) Polyclonal Antibody

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Catalog No. TMAC-00070

Anti-Phospho-ACK1 (Tyr284) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ACK1 (Tyr284). Anti-Phospho-ACK1 (Tyr284) Polyclonal Antibody can be used in WB,IHC,IF.

Anti-Phospho-ACK1 (Tyr284) Polyclonal Antibody

Anti-Phospho-ACK1 (Tyr284) Polyclonal Antibody

😃Good
Catalog No. TMAC-00070
Anti-Phospho-ACK1 (Tyr284) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ACK1 (Tyr284). Anti-Phospho-ACK1 (Tyr284) Polyclonal Antibody can be used in WB,IHC,IF.
Pack SizePriceAvailabilityQuantity
50 μL$2187-10 days
100 μL$3187-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-ACK1 (Tyr284) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ACK1 (Tyr284). Anti-Phospho-ACK1 (Tyr284) Polyclonal Antibody can be used in WB,IHC,IF.
Ig Type
IgG
Reactivity
Human,Mouse
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-100; IF: 1:100-200
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundNon-receptor tyrosine-protein and serine/threonine-protein kinase that is implicated in cell spreading and migration, cell survival, cell growth and proliferation. Transduces extracellular signals to cytosolic and nuclear effectors. Phosphorylates AKT1, AR, MCF2, WASL and WWOX. Implicated in trafficking and clathrin-mediated endocytosis through binding to epidermal growth factor receptor (EGFR) and clathrin. Binds to both poly- and mono-ubiquitin and regulates ligand-induced degradation of EGFR, thereby contributing to the accumulation of EGFR at the limiting membrane of early endosomes.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of tyrosine 284 (D-H-Y(p)-V-M) derived from Human ACK1
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 120 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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