Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-Osteopontin Antibody (6E962)

😃Good
Catalog No. TMAY-00675
Alias secreted phosphoprotein 1, OPN, ETA-1, BSPI, BNSP

Anti-Osteopontin Antibody (6E962) is a Rabbit antibody targeting Osteopontin. Anti-Osteopontin Antibody (6E962) can be used in ELISA.

Anti-Osteopontin Antibody (6E962)

Anti-Osteopontin Antibody (6E962)

😃Good
Catalog No. TMAY-00675Alias secreted phosphoprotein 1, OPN, ETA-1, BSPI, BNSP
Anti-Osteopontin Antibody (6E962) is a Rabbit antibody targeting Osteopontin. Anti-Osteopontin Antibody (6E962) can be used in ELISA.
Pack SizePriceAvailabilityQuantity
100 μL$269 7-10 days
Bulk & Custom
Add to Cart
Questions
View More
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Anti-Osteopontin Antibody (6E962) is a Rabbit antibody targeting Osteopontin. Anti-Osteopontin Antibody (6E962) can be used in ELISA.
Aliassecreted phosphoprotein 1, OPN, ETA-1, BSPI, BNSP
Ig Type
Monoclonal Rabbit IgG
Clone
6E962
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human Osteopontin / SPP1 / ETA-1 (rh Osteopontin / SPP1 / ETA-1; TMPY-01288; NP_001035147.1; Met 1-Asn 314) .
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundOsteopontin, also known as Secreted phosphoprotein 1, Bone sialoprotein 1, BSP-1, OPN, and SPP1, is a member of the osteopontin family and a SIBLING glycoprotein. Osteopontin has been classified as T-helper 1 cytokine and thus believed to exacerbate inflammation in several chronic inflammatory diseases, including atherosclerosis. Besides proinflammatory functions, physiologically Osteopontin is a potent inhibitor of mineralization, it prevents ectopic calcium deposits and is a potent inducible inhibitor of vascular calcification. Osteopontin is expressed and secreted by various cells, and has a role in cell adhesion, chemotaxis, prevention of apoptosis, invasion, migration and anchorage-independent growth of tumor cells. Osteopontin recruitment functions of inflammatory cells are thought to be mediated through its adhesive domains, especially the arginine-glycine-aspartate (RGD) sequence that interacts with several integrin heterodimers. Osteopontin has emerged as a potential biomarker and mediator in cardiovascular disease. In the context of atherosclerosis, OPN is generally regarded as a proinflammatory and proatherogenic molecule. However, the role of OPN in vascular calcification (VC), which is closely related to chronic and active inflammation, is that of a negative regulator because it is an inhibitor of calcification and an active inducer of decalcification. Extensive research has demonstrated the pivotal participation of Osteopontin in the regulation of cell signaling which controls neoplastic and malignant transformation. The elevated expression of Osteopontin has been observed in a variety of cancers. It has been linked with tumor metastasis and signifies a poor prognosis for the patient.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human Osteopontin / SPP1 / ETA-1 Protein (TMPY-01288)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

Sci Citations

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Anti-Osteopontin Antibody (6E962) | purchase Anti-Osteopontin Antibody (6E962) | Anti-Osteopontin Antibody (6E962) cost | order Anti-Osteopontin Antibody (6E962)