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Anti-IL-4R Antibody-APC (9B64) is a APC-conjugated Rabbit antibody targeting IL-4R. Anti-IL-4R Antibody-APC (9B64) can be used in FCM.
Description | Anti-IL-4R Antibody-APC (9B64) is a APC-conjugated Rabbit antibody targeting IL-4R. Anti-IL-4R Antibody-APC (9B64) can be used in FCM. |
Ig Type | Monoclonal Rabbit IgG |
Clone | 9B64 |
Reactivity | Rat |
Verified Activity | Flow cytometric analysis of rat IL4R expression on SD rat splenocytes. Cells were stained with APC-conjugated anti-rat IL4R. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
Application | FCM |
Recommended Dose | 5 μl/Test, 0.1 mg/ml |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Rat IL4R (rR IL4R; TMPY-02914; Q63257-1; Met1-Arg232) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
Purification | Protein A |
Appearance | Liquid |
Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
Research Background | The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alters the behavior of the cell. Some CD proteins do not take part in the cell signal process but have other functions such as cell adhesion. CD124, also known as the interleukin 4 receptor (IL4R), is a typeⅠ transmembrane protein that can regulate IgE antibody production in B cells through binding to interleukin 4 and interleukin 13 and promote differentiation of Th2 cells through binding to interleukin 4. The membrane-bound form of CD124 can be hydrolyzed to a soluble form which can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. |
Conjucates | APC |
Others Formats | Unconjugated/PE |
Antibody Types Available | 3 |
Immunogen | Recombinant Rat IL4R Protein (TMPY-02914) |
Antigen Species | Rat |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
Transport | Shipping with blue ice. |
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