Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-FKBP51 Antibody (6E556)

😃Good
Catalog No. TMAC-01490

Anti-FKBP51 Antibody (6E556) is a Rabbit antibody targeting FKBP51. Anti-FKBP51 Antibody (6E556) can be used in WB,IHC,ICC/IF,IP,FCM.

Anti-FKBP51 Antibody (6E556)

Anti-FKBP51 Antibody (6E556)

😃Good
Catalog No. TMAC-01490
Anti-FKBP51 Antibody (6E556) is a Rabbit antibody targeting FKBP51. Anti-FKBP51 Antibody (6E556) can be used in WB,IHC,ICC/IF,IP,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2977-10 days
100 μL$4967-10 days
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View More

Product Introduction

Bioactivity
Description
Anti-FKBP51 Antibody (6E556) is a Rabbit antibody targeting FKBP51. Anti-FKBP51 Antibody (6E556) can be used in WB,IHC,ICC/IF,IP,FCM.
Ig Type
IgG
Reactivity
Human,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC: 1:50-200; ICC/IF: 1:50-200; IP: 1:50; FCM: 1:50
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases that bind to and mediate the effects of immunosuppressive drugs, such as cyclosporin, FK506 and rapamycin. Several related immunophilins, FKBP12, FKBP51 and FKBP52, are characterized as cytosolic FK506-binding proteins, and following ligand binding, they functionally inhibit the phosphatase activity of calcineurin. The ubiquitously expressed FKBP12 also associates with the cytoplasmic domain of the TGFβ-type I receptor, where it stabilizes the inactive conformation of the receptor and blocks the activation of the TGFβ pathway. FKBP51 and FKBP52 are two highly related proteins. FKBP51 is predominantly expressed in T cells and is induced by glucocorticoids. FKBP51 mediates the effects of FK506 and rapamycin by inhibiting intracellular calcineurin activity, and by blocking T-cell activation and proliferation. FKBP52, known also as FKBP-59 or heat shock protein 56, is expressed in a variety of tissues and can also associate with the heat shock protein (hsp90) in mature steroid receptor complexes (6,8).
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Antigen Species
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 51 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Anti-FKBP51 Antibody (6E556) | purchase Anti-FKBP51 Antibody (6E556) | Anti-FKBP51 Antibody (6E556) cost | order Anti-FKBP51 Antibody (6E556) | Anti-FKBP51 Antibody (6E556) molecular weight