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SPK-601

Name: SPK-601
Brand: TargetMol
SKU: T16920
Rating: 4.5 (1 reviews)

😃Good

Catalog No. T16920Cas No. 1096687-52-3

Alias LMV-601

SPK-601 is an inhibitor of phosphatidylcholine-specific phospholipase C.

SPK-601

😃Good

Catalog No. T16920Alias LMV-601Cas No. 1096687-52-3

SPK-601 is an inhibitor of phosphatidylcholine-specific phospholipase C.

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$1,520	6-8 weeks	6-8 weeks
50 mg	$1,980	6-8 weeks	6-8 weeks
100 mg	$2,500	6-8 weeks	6-8 weeks

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	SPK-601 is an inhibitor of phosphatidylcholine-specific phospholipase C.
In vitro	SPK-601 (72 hours; HPV-31 cells) exhibits dose-dependent inhibition of cell growth (IC50: 16 μg/mL) and also inhibits HPV-31 specific RNA expression and DNA replication [2].
Synonyms	LMV-601

Chemical Properties

Molecular Weight	267.47
Formula	C₁₁H₁₆KOS₂
Cas No.	1096687-52-3
Smiles	[K].[H][C@]12CCC[C@@]1([H])[C@H]1C[C@@H]2C[C@@H]1OC(S)=S \|TLB:13:12:6.2:9,3:2:9:12.11,THB:5:6:9:12.11\|jcExt:v:0:0
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 5 mg/mL (18.69 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.7387 mL	18.6937 mL	37.3874 mL	186.9369 mL
5 mM	0.7477 mL	3.7387 mL	7.4775 mL	37.3874 mL
10 mM	0.3739 mL	1.8694 mL	3.7387 mL	18.6937 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc