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Anti-IL-17A Antibody-APC (2W545)
🥰Excellent
Catalog No. TMAY-03537A
Anti-IL-17A Antibody-APC (2W545) is a APC-conjugated Rabbit antibody targeting IL-17A. Anti-IL-17A Antibody-APC (2W545) can be used in FCM.
Anti-IL-17A Antibody-APC (2W545)
Anti-IL-17A Antibody-APC (2W545)
🥰Excellent
Catalog No. TMAY-03537A
Anti-IL-17A Antibody-APC (2W545) is a APC-conjugated Rabbit antibody targeting IL-17A. Anti-IL-17A Antibody-APC (2W545) can be used in FCM.
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Product Introduction
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Chemical Properties
| Description | Anti-IL-17A Antibody-APC (2W545) is a APC-conjugated Rabbit antibody targeting IL-17A. Anti-IL-17A Antibody-APC (2W545) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 2W545 |
| Reactivity | Mouse |
| Verified Activity | Flow cytometric analysis of Mouse IL17 expression on EL4 cells.The cells were stimulated for 4-6 hours with PMA and Ionomycin in the presence of GolgiPlug. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with APC-conjugated anti-Mouse IL17. The dot plots were derived from gated of intact cells. |
| Application | FCM |
| Recommended Dose | 10 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL-17A (rM IL-17A; TMPY-02900; Q62386; Thr22-Ala158) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| Research Background | IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune systems. The IL-17 family of cytokines includes six members, IL-17/IL-17A, IL-17B, IL-17C, IL-17D, IL-17E/IL-25, and IL-17F, which are produced by multiple cell types. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis, and multiple sclerosis.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | APC |
| Others Formats | Unconjugated/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Mouse IL-17A Protein (TMPY-02900) |
| Antigen Species | Mouse |
| Biology Area | Neuroinflammation |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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