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Glutathione reductase

Glutathione reductase catalyzes the reduction of glutathione disulfide (GSSG) to the sulfhydryl form glutathione (GSH), which is a critical molecule in resisting oxidative stress and maintaining the reducing environment of the cell.

L-Glutathione reduced
γ-L-Glutamyl-L-cysteinyl-glycine, Tathion, Isethion, GSH, Glutathione, Glutathion
T108570-18-8
L-Glutathione reduced (Glutathione) is a naturally occurring tripeptide found in cells as an endogenous antioxidant that scavenges oxygen free radicals. L-Glutathione reduced is a cofactor for certain enzymes and is involved in the rearrangement of protein disulfide bonds and the reduction of peroxides.
  • $32
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Glutathione oxidized
Oxidized glutathione, L-Glutathione oxidized, L(-)-Glutathione, GSSG, Glutathione disulfide, Bi(glutathion-S-yl)
T1085L27025-41-8
Glutathione oxidized (L(-) -glutathione) is the oxidized form of Glutathione, which is a major antioxidant and antidote in cells. Glutathione oxidized can be used to study sickle cells and red blood cells.
  • $39
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LCS3
T60446109844-92-0
LCS3 is a reversible and non-competitive synergistic inhibitor of glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) with IC50s of 3.3 μM and 3.8 μM, respectively. LCS3 has antitumour activity, induces apoptosis and can be used in the study of lung adenocarcinoma (LUAD).
  • $51
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Nitrofurazone
Nitrofural, NFZ, Furacilin
T089759-87-0
Nitrofurazone (Nitrofural; Furacilin) is an orally active nitroaromatic broad-spectrum antibiotic with activity against both Gram-positive and Gram-negative bacteria. It is commonly used for establishing breast cancer models.
  • $30
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Dantrolene-13C3
TMID-06561185234-99-4
Dantrolene-13C3 is the 13C3-labeled form of Dantrolene. Dantrolene (F368) serves as a muscle relaxant and non-competitively inhibits human erythrocyte glutathione reductase (glutathione reductase), exhibiting Ki and IC50 values of 111.6 μM and 52.3 μM, respectively. Additionally, Dantrolene acts as a ryanodine receptor antagonist and a stabilizer of Ca2+ signals. It is utilized in the treatment of muscle spasms and malignant hyperthermia.
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