ATG5 Protein, Human, Recombinant

Name: ATG5 Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPJ-01329
Price: 80 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: Autophagy protein 5, ATG5, ASP, Apoptosis-specific protein, APG5-like, APG5L) Copy Product Info

Synonyms: Autophagy protein 5, ATG5, ASP, Apoptosis-specific protein, APG5-like, APG5L

Catalog No. TMPJ-01329 Copy Product Info

ATG5 is an E2 ubiquitin ligase which is necessary for autophagy. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity, dramatically highly expressed in apoptotic cells. It is activated by ATG7, conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate complex detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 plays an important role in the apoptotic process, possibly within the modified cytoskeleton.

Pack Size	Price	USA Stock	Global Stock
5 µg	$80	-	In Stock
10 µg	$129	-	In Stock
20 µg	$198	-	In Stock
50 µg	$390	-	In Stock
100 µg	$626	-	In Stock
200 µg	$987	7-10 days	7-10 days
500 µg	$1,900	7-10 days	7-10 days
1 mg	$2,730	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:Greater than 90% as determined by reducing SDS-PAGE.

Appearance:Solution

Color:Transparent

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	ATG5 is an E2 ubiquitin ligase which is necessary for autophagy. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity, dramatically highly expressed in apoptotic cells. It is activated by ATG7, conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate complex detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 plays an important role in the apoptotic process, possibly within the modified cytoskeleton.
Species	Human
Expression System	E. coli
Tag	Tag Free
Accession Number	Q9H1Y0
Amino Acid	Met1-Asp275
Construction	Met1-Asp275
Protein Purity	Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 0.2M NaCl, 1 mM DTT, 40% Glycerol, pH 8.0.
Synonyms	Autophagy protein 5, ATG5, ASP, Apoptosis-specific protein, APG5-like, APG5L
Research Background	ATG5 is an E2 ubiquitin ligase which is necessary for autophagy. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity, dramatically highly expressed in apoptotic cells. It is activated by ATG7, conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate complex detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 plays an important role in the apoptotic process, possibly within the modified cytoskeleton.

Chemical Properties

Molecular Weight

33 KDa (reducing condition)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.