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Methylophiopogonanone A

🥰Excellent
Catalog No. T5S1262Cas No. 74805-92-8

1. Methylophiopogonanone A has anti-inflammatory and anti-oxidative properties. 2. Methylophiopogonanone A has therapeutic potential against cerebral I/R injury through its ability to attenuate BBB disruption by regulating the expression of MMP-9 and tight junction proteins.

Methylophiopogonanone A

Methylophiopogonanone A

🥰Excellent
Purity: 99.78%
Catalog No. T5S1262Cas No. 74805-92-8
1. Methylophiopogonanone A has anti-inflammatory and anti-oxidative properties. 2. Methylophiopogonanone A has therapeutic potential against cerebral I/R injury through its ability to attenuate BBB disruption by regulating the expression of MMP-9 and tight junction proteins.
Pack SizePriceAvailabilityQuantity
1 mg$72 In Stock
5 mg$168 In Stock
10 mg$250 In Stock
25 mg$418 In Stock
50 mg$623 In Stock
100 mg$887 In Stock
1 mL x 10 mM (in DMSO)$190 In Stock
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Purity:99.78%
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Product Introduction

Bioactivity
Description
1. Methylophiopogonanone A has anti-inflammatory and anti-oxidative properties. 2. Methylophiopogonanone A has therapeutic potential against cerebral I/R injury through its ability to attenuate BBB disruption by regulating the expression of MMP-9 and tight junction proteins.
Chemical Properties
Molecular Weight342.34
FormulaC19H18O6
Cas No.74805-92-8
SmilesCc1c(O)c(C)c2OC[C@@H](Cc3ccc4OCOc4c3)C(=O)c2c1O
Relative Density.1.411g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 60 mg/mL (175.26 mM), Sonication is recommended.
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble
In Vivo Formulation
10% DMSO+90% (20% SBE-β-CD in Saline): 2.5 mg/mL (7.3 mM)
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9211 mL14.6054 mL29.2107 mL146.0536 mL
5 mM0.5842 mL2.9211 mL5.8421 mL29.2107 mL
10 mM0.2921 mL1.4605 mL2.9211 mL14.6054 mL
20 mM0.1461 mL0.7303 mL1.4605 mL7.3027 mL
50 mM0.0584 mL0.2921 mL0.5842 mL2.9211 mL
100 mM0.0292 mL0.1461 mL0.2921 mL1.4605 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

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Keywords

Methylophiopogonanone AInhibitorinhibit
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