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CD27 Ligand/CD70 Protein, Cynomolgus, Recombinant (His)

TargetMol | SPR
Catalog No. TMPK-00666 Copy Product Info
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7.  CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. CD27 Ligand/CD70 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 18.4 kDa and the accession number is G7PYU6-1.

CD27 Ligand/CD70 Protein, Cynomolgus, Recombinant (His)

Catalog No. TMPK-00666
Copy Product Info
TargetMol | SPR

CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7.  CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. CD27 Ligand/CD70 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 18.4 kDa and the accession number is G7PYU6-1.

CD27 Ligand/CD70 Protein, Cynomolgus, Recombinant (His)
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$587-10 days7-10 days
10 μg$927-10 days7-10 days
20 μg$1487-10 days7-10 days
50 μg$2897-10 days7-10 days
100 μg$4877-10 days7-10 days
200 μg$8837-10 days7-10 days
500 μg$1,9507-10 days7-10 days
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In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

Product Information

Biological Activity
Immobilized Cynomolgus CD27 Ligand, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Cynomolgus/Rhesus macaque CD27, hFc Tag with the EC50 of 28.3ng/ml determined by ELISA.
Description
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7.  CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. CD27 Ligand/CD70 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 18.4 kDa and the accession number is G7PYU6-1.
Species
Cynomolgus
Expression System
HEK293 Cells
TagN-His
Accession NumberG7PYU6-1
Synonyms
TNFSF7G,TNFSF7,CD70 molecule,CD70,CD27LG,CD27-L,CD27 Ligand, Ki-24 antigen
Construction
Gln39-Pro194
Protein Purity
> 95% as determined by Tris-Bis PAGE
Molecular Weight18.4 kDa (predicted). Due to glycosylation, the protein migrates to 60-90 kDa based on Tris-Bis PAGE result.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution
Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Research Background
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7.  CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.

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