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TargetMol | Compound Library

Glycometabolism Compound Library

Catalog No. L2520

Glucose and glycogen are initial materials involved in the glycometabolism. A chronically irregular diet could result in the disorders of glycometabolism, which was manifested by the gradual deterioration of glucose tolerance over time, leading to the increased fasting blood glucose or impaired glucose tolerance. The clinical manifestations of glycometabolism-related disorder are hyperglycemia or hypoglycemia, which might eventually contribute to some serious diseases, such as diabetes, G6PD deficiency, obesity and malnutrition. In addition, favored glycolysis under aerobic conditions (aerobic glycolysis), or the Warburg effect, the transition from oxidative phosphorylation to glycolysis, accompanied by the accumulation of lactate by-products in the surrounding microenvironment and 20-30 times faster rate of glucose metabolism than the complete oxidation of glucose in the mitochondria, represents the most typical change observed in the metabolism of cancer cells. Therefore, a key to selective killing of cancer cells lies in their dependence on glycolysis. Targeting tumor cell metabolism has become a successful approach to the prevention or treatment of cancer. Most efforts have focused on the use of small molecules to inhibit the function of metabolic enzymes, which has been comprehensively reviewed elsewhere. Increasing evidence supports many glycolytic enzymes and transporters as candidates for cancer treatment. TargetMol's Glycometabolism Compound Library collects 1196 glycometabolism-related compounds, targeting GLUTs, Hexokinase(HK), Pyruvate Kinase(PK ), phosphofructokinase(PFK), IDH1/2, LDH, AMPK, etc. It is a powerful tool for research in glycometabolism-related disorders and cancer.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L2520

Glycometabolism Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • 1196 glycometabolism-related comounds, can be used for HTS and HCT;
  • Targets contain GLUTs、Hexokinase(HK)、Pyruvate Kinase(PK)、phosphofructokinase(PFK)、IDH1/2、LDH、AMPK, etc.;
  • Detailed compound information with structure, target, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality.
  • All compounds are in stock.

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

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Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
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Library Customization | TargetMol Library Composition

PI3K
Apoptosis
Autophagy
PPAR
Phosphatase
AMPK
GSK-3
mTOR
Mitochondrial Metabolism
Akt
HIF/HIF Prolyl-Hydroxylase
Carbonic Anhydrase
HIF
Endogenous Metabolite
p53
Dehydrogenase
CDK
Glucosidase
IGF-1R
Antibacterial
Glucokinase
DNA-PK
Reductase
Reactive Oxygen Species
DPP-4
NF-κB
PDK
S6 Kinase
SGLT
COX
transporter
Proteasome
Parasite
Ferroptosis
ATM/ATR
Glucocorticoid Receptor
Antibiotic
Src
ERK
PKC
Mdm2
Influenza Virus
HIV Protease
VEGFR
Calcium Channel
Isocitrate Dehydrogenase (IDH)
Cytochromes P450
NADPH
PKA
Wnt/beta-catenin
NAMPT
TNF
Potassium Channel
Antifungal
Mitophagy
MMP
MEK
SGK
PKM
PARP
PDE
DNA/RNA Synthesis
STAT
FLT
p38 MAPK
JNK
Virus Protease
IL Receptor
Chk
Aurora Kinase
Casein Kinase
PI4K
Tyrosinase
Antioxidant
ROCK
HSV
Lipoxygenase
Prostaglandin Receptor
Microtubule Associated
ATPase
PERK
Caspase
Bcr-Abl
ROS
Cholinesterase (ChE)
PTEN
Sirtuin
Bcl-2 Family
FGFR
FAK
TRP/TRPV Channel
Adrenergic Receptor
Aryl Hydrocarbon Receptor
E1/E2/E3 Enzyme
Hexokinase
PDGFR
Androgen Receptor
Interleukin
EGFR
MAPK
Nrf2
ALK
IκB/IKK
HDAC
AChR
Syk
NADPH-oxidase
Sodium Channel
Chloride channel
Estrogen/progestogen Receptor
c-Met/HGFR
DYRK
Amylase
SIK
Topoisomerase
Raf
Beta Amyloid
Reverse Transcriptase
GABA Receptor
Cannabinoid Receptor
GPCR
NOS
Transferase
Histone Methyltransferase
HCV Protease
Integrin
Adenosine Receptor
BACE
IFNAR
RAAS
Estrogen Receptor/ERR
HBV
Tyrosine Kinases
Serine Protease
MAO
Immunology/Inflammation related
LDL
Gamma-secretase
Drug Metabolite
Phosphorylase
ABC Transporter
Fatty Acid Synthase
DNA Alkylation
JAK
PAK
GluR
Epigenetic Reader Domain
TGF-beta/Smad
ATP Citrate Lyase
OXPHOS
Beta-Secretase
HSP
TLR
MELK
Retinoid Receptor
c-Fms
5-HT Receptor
Hydroxylase
PLK
c-RET
Anti-infection
DNA Methyltransferase
AhR
CFTR
NO Synthase
ADC Cytotoxin
Proton pump
NPC1L1
Monocarboxylate transporter
DHFR
Dopamine Receptor
Dynamin
MyD88
YAP
Arginase
DNA Alkylator/Crosslinker
Aconitase
Histone Demethylase
Histamine Receptor
Tie-2
gp120/CD4
Glutathione Peroxidase
GTPase
Progesterone Receptor
Cholecystokinin Receptor
Pim
Rho
Serine/threonin kinase
Cell Cycle Arrest
Cysteine Protease
Leukotriene Receptor
PYK2
Glutaminase
IAP
CSF-1R
iGluR
Myosin
FLAP
NMDAR
Antifection
Monoamine Transporter
Guanylate cyclase
Hedgehog/Smoothened
Bombesin Receptor
Epoxide Hydrolase
cAMP
CaMK
DUB
Lipid
BCRP
Acyltransferase
P-gp
STING
SARS-CoV
LRRK2
Trk receptor
Free radical scavengers
AIM2
CPT
Ligand for E3 Ligase
Aromatase
Phospholipase
Complement System
DAPK
c-Kit
NOD
Thrombin
NOD-like Receptor (NLR)
MLK
PD-1/PD-L1
S1P Receptor
PGC-1α