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Munc18-1/STXBP1 Protein, Human, Recombinant
(Synonyms: unc-18A, UNC18A, unc18-1, UNC18, RBSEC1, P67, N-Sec1, NSEC1, MUNC18-1, hUNC18, DEE4) Copy Product InfoSynonyms: unc-18A, UNC18A, unc18-1, UNC18, RBSEC1, P67, N-Sec1, NSEC1, MUNC18-1, hUNC18, DEE4
Catalog No. TMPY-07075 Copy Product Info
Munc18-1/STXBP1 Protein, Human, Recombinant is expressed in Baculovirus-Insect Cells. The accession number is P61764-1.
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $77 | - | In Stock | |
| 10 μg | $126 | - | In Stock | |
| 20 μg | $198 | 7-10 days | 7-10 days | |
| 50 μg | $397 | 7-10 days | 7-10 days | |
| 100 μg | $796 | 7-10 days | 7-10 days | |
| 200 μg | $1,200 | 7-10 days | 7-10 days | |
| 500 μg | $2,590 | 7-10 days | 7-10 days | |
| 1 mg | $5,280 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:≥ 85% as determined by SDS-PAGE.
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | Munc18-1/STXBP1 Protein, Human, Recombinant is expressed in Baculovirus-Insect Cells. The accession number is P61764-1. |
| Species | Human |
| Expression System | Baculovirus Insect Cells |
| Tag | Tag Free |
| Accession Number | P61764-1 |
| Construction | A DNA sequence encoding the Human STXBP1 (P61764-1) (Met1-Ser594) was expressed. |
| Protein Purity | ≥ 85% as determined by SDS-PAGE. |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10% Glycerol, pH 8.0. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Please refer to the lot-specific COA. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | unc-18A, UNC18A, unc18-1, UNC18, RBSEC1, P67, N-Sec1, NSEC1, MUNC18-1, hUNC18, DEE4 |
| Research Background | Syntaxin-binding protein 1, also known as N-Sec1, Protein unc-18 homolog 1, MUNC18-1 and STXBP1, is a peripheral membrane protein that belongs to the STXBP / unc-18 / SEC1 family. STXBP1 is an evolutionally conserved neuronal Sec1/Munc-18 (SM) protein that is essential in synaptic vesicle release in several species. It may participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. STXBP1 is essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. It can interact with syntaxins 1, 2, and 3 but not syntaxin 4. STXBP1 may also play a role in determining the specificity of intracellular fusion reactions. Defects in STXBP1 are the cause of epileptic encephalopathy early infantile type 4 (EIEE4). Affected individuals have neonatal or infantile onset of seizures, suppression-burst pattern on EEG, profound mental retardation, and MRI evidence of hypomyelination. |
| Molecular Weight | 67.73 kDa (predicted); 62.5 kDa (reducing contition, due to glycosylation) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Munc18-1/STXBP1 Protein, Human, Recombinant chemical structure | Munc18-1/STXBP1 Protein, Human, Recombinant molecular weight
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