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Propamidine isethionate

Name: Propamidine isethionate
Brand: TargetMol
SKU: T34144
Price: 185 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T34144 Copy Product Info

Purity: 99.98%

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Propamidine isethionate is an agent in the diamidine class with potent antibacterial and antiprotozoal properties. It is a critical reagent in the research and treatment of Acanthamoeba keratitis. Propamidine exerts its effects by binding to DNA and interfering with nucleic acid synthesis in pathogens.

Propamidine isethionate

Copy Product Info

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Catalog No. T34144

Cas No. 140-63-6

Pack Size	Price	USA Stock	Global Stock
5 mg	$185	-	In Stock
10 mg	$297	-	In Stock
25 mg	$596	-	In Stock
50 mg	$953	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.98%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Propamidine isethionate is an agent in the diamidine class with potent antibacterial and antiprotozoal properties. It is a critical reagent in the research and treatment of Acanthamoeba keratitis. Propamidine exerts its effects by binding to DNA and interfering with nucleic acid synthesis in pathogens.
In vitro	Propamidine isethionate is effective against Acanthamoeba trophozoites [1][2].

Chemical Properties

Molecular Weight	438.50
Formula	C₁₉H₂₆N₄O₆S
Cas No.	140-63-6
Smiles	OCCS(O)(=O)=O.NC(=N)c1ccc(OCCCOc2ccc(cc2)C(N)=N)cc1
Relative Density.	no data available

Storage & Solubility Information

Storage

Keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (228.05 mM), Sonication is recommmended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2805 mL	11.4025 mL	22.8050 mL	114.0251 mL
5 mM	0.4561 mL	2.2805 mL	4.5610 mL	22.8050 mL
10 mM	0.2281 mL	1.1403 mL	2.2805 mL	11.4025 mL
20 mM	0.1140 mL	0.5701 mL	1.1403 mL	5.7013 mL
50 mM	0.0456 mL	0.2281 mL	0.4561 mL	2.2805 mL
100 mM	0.0228 mL	0.1140 mL	0.2281 mL	1.1403 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc