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Dp3-Sam chloride

Name: Dp3-Sam chloride
Brand: TargetMol
SKU: TN1566
Rating: 4.5 (1 reviews)

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Catalog No. TN1566Cas No. 53158-73-9

Alias Delphinidin-3-sambubioside chloride

Dp3-Sam chloride (Delphinidin-3-sambubioside chloride) is an anthocyanin from Hibiscus acetosella (Cranberry Hibiscus) with anti-inflammatory, antioxidant, and anticancer activities.Dp3-Sam chloride inhibits LPS-induced inflammation, and inhibits LPS-induced inflammation. Dp3-Sam chloride inhibits LPS-induced inflammatory factor release, down-regulates the NF-κB pathway, and inhibits MEK1/2-ERK1/2 signaling.Dp3-Sam chloride induces apoptosis in human leukemia cells through the mitochondrial pathway mediated by reactive oxygen species.

Dp3-Sam chloride

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Catalog No. TN1566Alias Delphinidin-3-sambubioside chlorideCas No. 53158-73-9

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
5 mg	$611	7-10 days	7-10 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Appearance:Solid

Color:Purple to Black

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Product Introduction

Bioactivity

Description	Dp3-Sam chloride (Delphinidin-3-sambubioside chloride) is an anthocyanin from Hibiscus acetosella (Cranberry Hibiscus) with anti-inflammatory, antioxidant, and anticancer activities.Dp3-Sam chloride inhibits LPS-induced inflammation, and inhibits LPS-induced inflammation. Dp3-Sam chloride inhibits LPS-induced inflammatory factor release, down-regulates the NF-κB pathway, and inhibits MEK1/2-ERK1/2 signaling.Dp3-Sam chloride induces apoptosis in human leukemia cells through the mitochondrial pathway mediated by reactive oxygen species.
In vitro	Dp3-Sam chloride (50-200 μM, 30 min) inhibits LPS-induced iNOS expression, suppresses the phosphorylation of ERK1/2 and MEK1/2, and downregulates the NF-κB signaling pathway in RAW264.7 cells[1]. Dp3-Sam chloride (24 h) inhibits HL-60 cells proliferation by inducing apoptosis (IC50 of 75 μM).[2] Dp3-Sam chloride (100-200 µg/mL, 24 h) decreases intracellular TG levels and lipid accumulation in oleic acid-treated HepG2 cells.[2]
In vivo	Dp3-Sam chloride (15 μmol/kg; i.p.; mouse) reduced the LPS-induced paw thickness and decreased the edema by 89.3%.[1] Dp3-Sam chloride (30 mg/kg body; oral gavage; daily for eight weeks) decreases lipid accumulation in HFD rats and decreases LPS-induced serum IL-6, MCP-1, and TNF-α levels.[3]
Synonyms	Delphinidin-3-sambubioside chloride

Chemical Properties

Molecular Weight	632.95
Formula	C₂₆H₂₉ClO₁₆
Cas No.	53158-73-9
Smiles	O(C=1C(=[O+]C2=C(C1)C(O)=CC(O)=C2)C3=CC(O)=C(O)C(O)=C3)[C@H]4[C@H](O[C@H]5[C@H](O)[C@@H](O)[C@H](O)CO5)[C@@H](O)[C@H](O)[C@@H](CO)O4.[Cl-]
Relative Density.	no data available

Storage & Solubility Information

Storage

keep away from direct sunlight,store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc