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Anti-RAP1GAP Monoclonal Antibody (1L49)
(Synonyms: RAPGAP, RAP1GAPII, RAP1GAP1, RAP1GA1) Copy Product Info
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Synonyms: RAPGAP, RAP1GAPII, RAP1GAP1, RAP1GA1
Catalog No. TMAC-03533 Copy Product Info
🥰Excellent
Anti-RAP1GAP Monoclonal Antibody (1L49) is a Mouse antibody targeting RAP1GAP. Anti-RAP1GAP Monoclonal Antibody (1L49) can be used in FCM.
Anti-RAP1GAP Monoclonal Antibody
(1L49)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 µL | $296 | 7-10 days | 7-10 days | |
| 100 µL | $427 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-RAP1GAP Monoclonal Antibody (1L49) is a Mouse antibody targeting RAP1GAP. Anti-RAP1GAP Monoclonal Antibody (1L49) can be used in FCM. |
| Synonyms | RAPGAP, RAP1GAPII, RAP1GAP1, RAP1GA1 |
| Ig Type | IgG2b |
| Clone | 1L49 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of A431 cells with RAP1GAP antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).  |
| Application | |
| Recommended Dose | FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form. The product of this gene, RAP1GAP, promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins, guanine nucleotide exchange factors (GEFs), act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form. In general, ras subfamily proteins, such as RAP1, play key roles in receptor-linked signaling pathways that control cell growth and differentiation. RAP1 plays a role in diverse processes such as cell proliferation, adhesion, differentiation, and embryogenesis. Alternative splicing results in multiple transcript variants encoding distinct proteins. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human RAP1GAP (AA: 412-660) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | RAP1GAP |
| Gene ID | |
| Protein Name | Rap1 GTPase-activating protein 1 |
| Uniprot ID |
| Molecular Weight | Theoretical: 73 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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