Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Filipin II is a polyene and an active component of the polyene antibiotic filipin complex . [1] It has broad-spectrum antifungal activity, reducing growth of various fungi, including B. dermatitidis, C. neoformans, and H. capsulatum (MICs = 1-10 μg/ml). Filipin II inhibits ADP-stimulated respiration in rat liver mitochondria when used at a concentration of 3.5 mg/ml. [2] It also induces hemolysis of liposomes in a cholesterol-independent manner (IC50 = 0.5 μg/ml).[3]
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 μg | 35 days | $ 623.00 |
Description | Filipin II is a polyene and an active component of the polyene antibiotic filipin complex . [1] It has broad-spectrum antifungal activity, reducing growth of various fungi, including B. dermatitidis, C. neoformans, and H. capsulatum (MICs = 1-10 μg/ml). Filipin II inhibits ADP-stimulated respiration in rat liver mitochondria when used at a concentration of 3.5 mg/ml. [2] It also induces hemolysis of liposomes in a cholesterol-independent manner (IC50 = 0.5 μg/ml).[3] |
Molecular Weight | 638.839 |
Formula | C35H58O10 |
CAS No. | 38620-77-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: Soluble
DMSO: Soluble
Methanol: Soluble
DMF: Soluble
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Filipin II 38620-77-8 inhibitor inhibit