Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Porfiromycin is a n N-methyl derivative of the antineoplastic antibiotic mitomycin C isolated from the bacterium Streptomyces ardus and other Streptomyces bacterial species. Bioreduced porfiromycin generates oxygen radicals and alkylates DNA, producing interstrand cross-links and single-strand breaks, thereby inhibiting DNA synthesis. Porfiromycin is preferentially toxic to hypoxic cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | Porfiromycin is a n N-methyl derivative of the antineoplastic antibiotic mitomycin C isolated from the bacterium Streptomyces ardus and other Streptomyces bacterial species. Bioreduced porfiromycin generates oxygen radicals and alkylates DNA, producing interstrand cross-links and single-strand breaks, thereby inhibiting DNA synthesis. Porfiromycin is preferentially toxic to hypoxic cells. |
Molecular Weight | 348.35 |
Formula | C16H20N4O5 |
CAS No. | 801-52-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Porfiromycin 801-52-5 porfiromycine porphyromycin Nmethylmitomycin C. U14743 Methylmitomycin US brand name: Promycin. Code names: ENT50825 methyl mitomycin C inhibitor inhibit