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Anti-PBK/TOPK Antibody (6C84)
(Synonyms: TOPK, SPK, PDZ binding kinase, Nori-3, HEL164, CT84) Copy Product Info
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Synonyms: TOPK, SPK, PDZ binding kinase, Nori-3, HEL164, CT84
Catalog No. TMAC-03090 Copy Product Info
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Anti-PBK/TOPK Antibody (6C84) is a Mouse antibody targeting PBK/TOPK. Anti-PBK/TOPK Antibody (6C84) can be used in FCM,ICC,IHC,WB.
Anti-PBK/TOPK Antibody
(6C84)
(6C84)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $428 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
Stability & Storage
| Description | Anti-PBK/TOPK Antibody (6C84) is a Mouse antibody targeting PBK/TOPK. Anti-PBK/TOPK Antibody (6C84) can be used in FCM,ICC,IHC,WB. |
| Synonyms | TOPK, SPK, PDZ binding kinase, Nori-3, HEL164, CT84 |
| Clone | 6C84 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500; IHC: 1:100-500; ICC: 1:100-500; FCM: 1:100-200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
| Research Background | Protein kinases comprise a large group of encoded factors that regulate cellular processes by catalyzing the transfer of a phosphate group to a hydroxyl acceptor in serine, threonine or tyrosine residues. Kinases are capable of influencing the oncogenic potential of cell sytems at the level of oncoprotein or tumor suppressor protein phosphorylation states. Human PDZ-binding kinase, known as PBK, is a 322 amino acid, T/SXV motif-containing serine/threonine kinase that is abuntant in placenta and absent from adult brain tissue. A PDZ domain in the tumor suppressor protein Dlg can coordinate with the T/SXV motif of PBK. The cell cycle checkpoint kinase Cdc2/cyclin B is an upstream effector of PBK that can phosphorylate and activate PBK. Active PBK may associate with PDZ-containing proteins and influence cell cycle control or cellular proliferation. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 36 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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