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alpha-Methyl-p-tyrosine methyl ester hydrochloride

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Catalog No. T64983Cas No. 7361-31-1
Alias α-Methyltyrosine methyl ester hydrochloride, Tyrosine, alpha-methyl-, methyl ester, hydrochloride

alpha-Methyl-p-tyrosine methyl ester hydrochloride is a biochemical reagent exhibiting inhibitory activity and oral bioavailability towards tyrosine hydroxylase. It suppresses the conversion of tyrosine to dopamine and may be employed in neurological research.

alpha-Methyl-p-tyrosine methyl ester hydrochloride

alpha-Methyl-p-tyrosine methyl ester hydrochloride

🥰Excellent
Catalog No. T64983Alias α-Methyltyrosine methyl ester hydrochloride, Tyrosine, alpha-methyl-, methyl ester, hydrochlorideCas No. 7361-31-1
alpha-Methyl-p-tyrosine methyl ester hydrochloride is a biochemical reagent exhibiting inhibitory activity and oral bioavailability towards tyrosine hydroxylase. It suppresses the conversion of tyrosine to dopamine and may be employed in neurological research.
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Product Introduction

Bioactivity
Description
alpha-Methyl-p-tyrosine methyl ester hydrochloride is a biochemical reagent exhibiting inhibitory activity and oral bioavailability towards tyrosine hydroxylase. It suppresses the conversion of tyrosine to dopamine and may be employed in neurological research.
In vivo
Rats were orally administered 200–1000 mg/kg of alpha-Methyl-p-tyrosine methyl ester hydrochloride daily for 4 consecutive weeks, which could induce kidney injury and lead to the formation of urinary tract stones. [1]
Synonymsα-Methyltyrosine methyl ester hydrochloride, Tyrosine, alpha-methyl-, methyl ester, hydrochloride
Chemical Properties
Molecular Weight245.70
FormulaC11H16ClNO3
Cas No.7361-31-1
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 3.50 mg/mL (14.25 mM), Sonication is recommended.
H2O: 8.00 mg/mL (32.56 mM), Sonication is recommended.
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM4.0700 mL20.3500 mL40.7000 mL203.5002 mL
5 mM0.8140 mL4.0700 mL8.1400 mL40.7000 mL
10 mM0.4070 mL2.0350 mL4.0700 mL20.3500 mL
H2O
1mg5mg10mg50mg
20 mM0.2035 mL1.0175 mL2.0350 mL10.1750 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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