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Anti-Her2/ERBB2 Antibody-APC (5S123)
🥰Excellent
Catalog No. TMAY-00035A
Anti-Her2/ERBB2 Antibody-APC (5S123) is a APC-conjugated Mouse antibody targeting Her2/ERBB2. Anti-Her2/ERBB2 Antibody-APC (5S123) can be used in FCM.
Anti-Her2/ERBB2 Antibody-APC (5S123)
Anti-Her2/ERBB2 Antibody-APC (5S123)
🥰Excellent
Catalog No. TMAY-00035A
Anti-Her2/ERBB2 Antibody-APC (5S123) is a APC-conjugated Mouse antibody targeting Her2/ERBB2. Anti-Her2/ERBB2 Antibody-APC (5S123) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Her2/ERBB2 Antibody-APC (5S123) is a APC-conjugated Mouse antibody targeting Her2/ERBB2. Anti-Her2/ERBB2 Antibody-APC (5S123) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 5S123 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of anti-Human ErbB2 on SKBR3 cells. |
| Application | FCM |
| Recommended Dose | 2 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This product is a recombinant monoclonal antibody expressed from HEK293 cells. Then conjugated with APC under optimum conditions, the unreacted APC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand binding and enhances kinase-mediated activation of downstream molecules. HER2 plays a key role in development, cell proliferation and differentiation. HER2 gene has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | APC |
| Others Formats | Unconjugated/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Human ErbB2 / HER2 / CD340 protein (TMPY-01137) |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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