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CM-TPMF

🥰Excellent
Catalog No. T27053Cas No. 477865-59-1
Alias CMTPMF, CM TPMF

CM-TPMF is a highly efficient and potent activator of the K(Ca)2.1 channel, with an EC50 value of 24 nM for (-)CM-TPMF, which exerts its activating effect through Ser293 in the transmembrane segment 5, and can be used for research into related neurological disorders.

CM-TPMF

CM-TPMF

🥰Excellent
Purity: 99.94%
Catalog No. T27053Alias CMTPMF, CM TPMFCas No. 477865-59-1
CM-TPMF is a highly efficient and potent activator of the K(Ca)2.1 channel, with an EC50 value of 24 nM for (-)CM-TPMF, which exerts its activating effect through Ser293 in the transmembrane segment 5, and can be used for research into related neurological disorders.
Pack SizePriceAvailabilityQuantity
1 mg$293In Stock
5 mg$722In Stock
10 mg$987In Stock
25 mg$1,520In Stock
50 mg$1,980In Stock
100 mg$2,500In Stock
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Purity:99.94%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
CM-TPMF is a highly efficient and potent activator of the K(Ca)2.1 channel, with an EC50 value of 24 nM for (-)CM-TPMF, which exerts its activating effect through Ser293 in the transmembrane segment 5, and can be used for research into related neurological disorders.
SynonymsCMTPMF, CM TPMF
Chemical Properties
Molecular Weight360.8
FormulaC16H17ClN6O2
Cas No.477865-59-1
SmilesClC1=CC=C(OC(C2=CC=NC3=NC(=NN32)NC=NOC)C)C(=C1)C
Relative Density.1.39 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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2 Enter the in vivo formulation:
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CM-TPMF
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