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Cristacarpin is a natural product with antibacterial and anticancer activity that promotes endoplasmic reticulum stress and ROS production.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $770 | In Stock |
Description | Cristacarpin is a natural product with antibacterial and anticancer activity that promotes endoplasmic reticulum stress and ROS production. |
In vitro | Methods AND Results: Bioactivity-directed fractionation of the CHCl3 extract of the bark of Erythrina burana afforded phaseollidin [1] and Cristacarpin [2]. Both 1 and Cristacarpin exhibited moderate but selective activity towards DNA repair-deficient yeast mutants, whereas only 1 was found to be cytotoxic. 13C-nmr spectra of both compounds were assigned. |
In vivo | Methods: Cristacarpin (0.1-10 μM) was used to treat three different moderately invasive cell lines, PANC-1, MCF-7 and PC3, and cell proliferation was determined by MTT. Results: The IC50 values of Cristacarpin for the three cell lines were 6.3, 6.6 and 10.23 μM. [3] |
Alias | Erythrabyssin I, Erythrabissin I |
Molecular Weight | 354.4 |
Formula | C21H22O5 |
Cas No. | 74515-47-2 |
Smiles | O[C@]12[C@](C=3C(OC1)=CC(O)=CC3)(OC=4C2=CC=C(OC)C4CC=C(C)C)[H] |
Relative Density. | no data available |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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