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Anti-Engrailed 1 Polyclonal Antibody

(Synonyms: Mo-en.1, Hu-En-1, Homeobox protein engrailed 1, Homeobox protein en-1, HME1, Engrailed1, Engrailed homolog 1, Engrailed homeobox 1, Engrailed, EN1/Engrailed 1, EN-1, EN1) Copy Product Info
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Synonyms: Mo-en.1, Hu-En-1, Homeobox protein engrailed 1, Homeobox protein en-1, HME1, Engrailed1, Engrailed homolog 1, Engrailed homeobox 1, Engrailed, EN1/Engrailed 1, EN-1, EN1

Catalog No. TMAB-00613 Copy Product Info
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Anti-Engrailed 1 Polyclonal Antibody is a Rabbit antibody targeting Engrailed 1. Anti-Engrailed 1 Polyclonal Antibody can be used in FCM, WB.
Anti-Engrailed 1 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Engrailed 1 Polyclonal Antibody is a Rabbit antibody targeting Engrailed 1. Anti-Engrailed 1 Polyclonal Antibody can be used in FCM, WB.
SynonymsMo-en.1, Hu-En-1, Homeobox protein engrailed 1, Homeobox protein en-1, HME1, Engrailed1, Engrailed homolog 1, Engrailed homeobox 1, Engrailed, EN1/Engrailed 1, EN-1, EN1
Ig Type
IgG
Reactivity
Human,Mouse,Rat (predicted:Chicken,Dog,Pig,Cow,Horse,Sheep,Rabbit)
Application
Recommended Dose
WB: 1:500-2000; FCM: 1μg/Test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundThe engrailed-1 gene, EN1, a murine homolog of the Drosophila homeobox gene engrailed (EN), is required for midbrain and cerebellum development and dorsal/ventral patterning of the limbs as well as apical ectodermal ridge formation. In Drosophila, the EN gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Human EN-1 and EN-2 are homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. Different mutations in the mouse homo-logs, EN-1 and EN-2, produce different developmental defects that frequently are lethal. EN-1 is highly expressed by essentially all dopaminergic neurons in the substantia nigra and ventral tegmentum. EN-1 and EN-2 regulate expres-sion of a-synuclein, a gene that is genetically linked to Parkinson’s disease.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human EN1/Engrailed 1
Antigen Species
Human
Gene Name
EN1
Gene ID
Protein Name
Homeobox protein engrailed-1
Uniprot ID
Biology Area
Nuclear,Ectoderm,Neurogenesis,Other factors,Developmental Families,Ectoderm
Chemical Properties
Molecular WeightTheoretical: 40 kDa. Actual: 50 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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