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Anti-GLI1 Polyclonal Antibody
(Synonyms: Zinc finger protein GLI1, Oncogene GLI, Glioma-associated oncogene, GLI1, GLI) Copy Product Info
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Synonyms: Zinc finger protein GLI1, Oncogene GLI, Glioma-associated oncogene, GLI1, GLI
Catalog No. TMAB-00775 Copy Product Info
🥰Excellent
Anti-GLI1 Polyclonal Antibody is a Rabbit antibody targeting GLI1. Anti-GLI1 Polyclonal Antibody can be used in FCM,IF,IHC-Fr,IHC-P,WB.
Anti-GLI1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-GLI1 Polyclonal Antibody is a Rabbit antibody targeting GLI1. Anti-GLI1 Polyclonal Antibody can be used in FCM,IF,IHC-Fr,IHC-P,WB. |
| Synonyms | Zinc finger protein GLI1, Oncogene GLI, Glioma-associated oncogene, GLI1, GLI |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Dog,Cow,Horse,Rabbit) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1ug/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Nucleus. Tethered in the cytoplasm by binding to SUFU. Activation and translocation to the nucleus is promoted by interaction with STK36. Phosphorylation by ULK3 may promote nuclear localization. Translocation to the nucleus is promoted by interaction with ZIC1. |
| Tissue Specificity | Testis, myometrium and fallopian tube. Also expressed in the brain with highest expression in the cerebellum, optic nerve and olfactory tract. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] |
| Immunogen | KLH conjugated synthetic peptide: human GLI1/Zfp5 |
| Antigen Species | Human |
| Gene Name | GLI1 |
| Gene ID | |
| Protein Name | Zinc finger protein GLI1 |
| Uniprot ID | |
| Biology Area | PTC & Wnt pathway,Krueppel like factor,Zinc Finger,Neural Signal Transduction,Nuclear |
| Function | Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation. |
| Molecular Weight | Theoretical: 118 kDa. Actual: 130 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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