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IL-10R alpha/IL-10RA Protein, Macaca mulatta, Recombinant (His)

Catalog No. TMPJ-01424
Synonyms: IL-10RA, Interleukin-10 receptor subunit 1, IL-10R subunit 1, IL-10R subunit alpha, Interleukin-10 receptor subunit α, IL-10 receptor subunit α, IL-10 receptor subunit alpha, IL-10R1, IL10RA, IL-10R subunit α, CDw210a, CD210, Interleukin-10 receptor subunit alpha

Interleukin-10 Receptor alpha (IL-10 R alpha), also known as IL-10 R1, is transmembrane glycoprotein member of the class II cytokine receptor family. Interleukin-10 (IL10) is a key anti-inflammatory cytokine that is produced predominantly by leukocytes including T cells, B cells, monocytes, macrophages, and dendritic cells (DCs), as well as by some epithelial cells. The receptor for IL10 is a heterotetramer complex comprising two IL10Ra (also referred to as IL10R1) molecules and two IL10Rb (also referred to as IL10R2) molecules.IL10Ra is expressed on most hematopoietic cells at a basal level but is upregulated by various cells upon activation, suggesting its importance in inhibitory pathways.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
IL-10R alpha/IL-10RA Protein, Macaca mulatta, Recombinant (His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 147.00
50 μg 5 days $ 449.00
500 μg 5 days $ 2,640.00
1 mg 5 days $ 3,960.00
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Biological Description
Technical Params
Product Properties
Description Interleukin-10 Receptor alpha (IL-10 R alpha), also known as IL-10 R1, is transmembrane glycoprotein member of the class II cytokine receptor family. Interleukin-10 (IL10) is a key anti-inflammatory cytokine that is produced predominantly by leukocytes including T cells, B cells, monocytes, macrophages, and dendritic cells (DCs), as well as by some epithelial cells. The receptor for IL10 is a heterotetramer complex comprising two IL10Ra (also referred to as IL10R1) molecules and two IL10Rb (also referred to as IL10R2) molecules.IL10Ra is expressed on most hematopoietic cells at a basal level but is upregulated by various cells upon activation, suggesting its importance in inhibitory pathways.
Species Macaca Mulatta
Expression System Human Cells
Tag C-6His
Accession Number XP_028689862.1
Synonyms IL-10RA, Interleukin-10 receptor subunit 1, IL-10R subunit 1, IL-10R subunit alpha, Interleukin-10 receptor subunit α, IL-10 receptor subunit α, IL-10 receptor subunit alpha, IL-10R1, IL10RA, IL-10R subunit α, CDw210a, CD210, Interleukin-10 receptor subunit alpha
Amino Acid His22-Asn235
Construction Recombinant Macaca Mulatta Interleukin-10 Receptor Subunit Alpha is produced by our Mammalian expression system and the target gene encoding His22-Asn235 is expressed with a 6His tag at the C-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 35-55 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Research Background Interleukin-10 Receptor alpha (IL-10 R alpha), also known as IL-10 R1, is transmembrane glycoprotein member of the class II cytokine receptor family. Interleukin-10 (IL10) is a key anti-inflammatory cytokine that is produced predominantly by leukocytes including T cells, B cells, monocytes, macrophages, and dendritic cells (DCs), as well as by some epithelial cells. The receptor for IL10 is a heterotetramer complex comprising two IL10Ra (also referred to as IL10R1) molecules and two IL10Rb (also referred to as IL10R2) molecules.IL10Ra is expressed on most hematopoietic cells at a basal level but is upregulated by various cells upon activation, suggesting its importance in inhibitory pathways.

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Keywords

IL-10R alpha/IL-10RA Protein, Macaca mulatta, Recombinant (His) CD 210 IL-10RA Interleukin-10 receptor subunit 1 IL-10R subunit 1 IL-10R subunit alpha Interleukin-10 receptor subunit α IL-10 receptor subunit α CD-210 IL-10 receptor subunit alpha IL-10R1 IL10RA IL-10R subunit α CDw210a CD210 Interleukin-10 receptor subunit alpha recombinant recombinant-proteins proteins protein

 

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