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IL-10R alpha/IL-10RA Protein, Macaca mulatta, Recombinant (His)

(Synonyms: Interleukin-10 receptor subunit α, Interleukin-10 receptor subunit alpha, Interleukin-10 receptor subunit 1, IL-10RA, IL10RA, IL-10R1, IL-10R subunit α, IL-10R subunit alpha, IL-10R subunit 1, IL-10 receptor subunit α, IL-10 receptor subunit alpha, CDw210a, CD210) Copy Product Info

Synonyms: Interleukin-10 receptor subunit α, Interleukin-10 receptor subunit alpha, Interleukin-10 receptor subunit 1, IL-10RA, IL10RA, IL-10R1, IL-10R subunit α, IL-10R subunit alpha, IL-10R subunit 1, IL-10 receptor subunit α, IL-10 receptor subunit alpha, CDw210a, CD210

Catalog No. TMPJ-01424 Copy Product Info
Interleukin-10 Receptor alpha (IL-10 R alpha), also known as IL-10 R1, is transmembrane glycoprotein member of the class II cytokine receptor family. Interleukin-10 (IL10) is a key anti-inflammatory cytokine that is produced predominantly by leukocytes including T cells, B cells, monocytes, macrophages, and dendritic cells (DCs), as well as by some epithelial cells. The receptor for IL10 is a heterotetramer complex comprising two IL10Ra (also referred to as IL10R1) molecules and two IL10Rb (also referred to as IL10R2) molecules.IL10Ra is expressed on most hematopoietic cells at a basal level but is upregulated by various cells upon activation, suggesting its importance in inhibitory pathways.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$917-10 days7-10 days
10 µg$1477-10 days7-10 days
20 µg$2367-10 days7-10 days
50 µg$4497-10 days7-10 days
100 µg$7637-10 days7-10 days
200 µg$1,2807-10 days7-10 days
500 µg$2,6307-10 days7-10 days
1 mg$3,9607-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Interleukin-10 Receptor alpha (IL-10 R alpha), also known as IL-10 R1, is transmembrane glycoprotein member of the class II cytokine receptor family. Interleukin-10 (IL10) is a key anti-inflammatory cytokine that is produced predominantly by leukocytes including T cells, B cells, monocytes, macrophages, and dendritic cells (DCs), as well as by some epithelial cells. The receptor for IL10 is a heterotetramer complex comprising two IL10Ra (also referred to as IL10R1) molecules and two IL10Rb (also referred to as IL10R2) molecules.IL10Ra is expressed on most hematopoietic cells at a basal level but is upregulated by various cells upon activation, suggesting its importance in inhibitory pathways.
Species
Macaca Mulatta
Expression System
HEK293 Cells
TagC-6xHis
Accession NumberXP_028689862.1
Amino AcidHis22-Asn235
ConstructionHis22-Asn235
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsInterleukin-10 receptor subunit α, Interleukin-10 receptor subunit alpha, Interleukin-10 receptor subunit 1, IL-10RA, IL10RA, IL-10R1, IL-10R subunit α, IL-10R subunit alpha, IL-10R subunit 1, IL-10 receptor subunit α, IL-10 receptor subunit alpha, CDw210a, CD210
Research Background
Interleukin-10 Receptor alpha (IL-10 R alpha), also known as IL-10 R1, is transmembrane glycoprotein member of the class II cytokine receptor family. Interleukin-10 (IL10) is a key anti-inflammatory cytokine that is produced predominantly by leukocytes including T cells, B cells, monocytes, macrophages, and dendritic cells (DCs), as well as by some epithelial cells. The receptor for IL10 is a heterotetramer complex comprising two IL10Ra (also referred to as IL10R1) molecules and two IL10Rb (also referred to as IL10R2) molecules.IL10Ra is expressed on most hematopoietic cells at a basal level but is upregulated by various cells upon activation, suggesting its importance in inhibitory pathways.
Chemical Properties
Molecular Weight35-55 KDa (reducing condition)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: IL-10R alpha/IL-10RA Protein, Macaca mulatta, Recombinant (His) chemical structure | IL-10R alpha/IL-10RA Protein, Macaca mulatta, Recombinant (His) molecular weight