PRDX3 Protein, Human, Recombinant

Name: PRDX3 Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPJ-00934
Rating: 4.5 (1 reviews)

(Synonyms: Thioredoxin-Dependent Peroxide Reductase Mitochondrial, Prx-III, Protein MER5 homolog, PRDX3, Peroxiredoxin-3, Peroxiredoxin III, HBC189, AOP-1, AOP1, Antioxidant Protein 1) Copy Product Info

Synonyms: Thioredoxin-Dependent Peroxide Reductase Mitochondrial, Prx-III, Protein MER5 homolog, PRDX3, Peroxiredoxin-3, Peroxiredoxin III, HBC189, AOP-1, AOP1, Antioxidant Protein 1

Catalog No. TMPJ-00934 Copy Product Info

Thioredoxin-Dependent Peroxide Reductase Mitochondrial (PRDX3) is an enzyme that belongs to the AhpC/TSA family. Human and mouse PRDX3 genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Human PRDX3 protein has an antioxidant function and is localized in the mitochondrion. PRDX3 is involved in redox regulation of the cell. PRDX3 protects radical-sensitive enzymes from oxidative damage by a radical-generating system. It acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.

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Pack Size	Price	USA Stock	Global Stock
10 µg	$116	7-10 days	7-10 days
20 µg	$186	7-10 days	7-10 days
50 µg	$352	7-10 days	7-10 days
100 µg	$582	7-10 days	7-10 days
200 µg	$967	7-10 days	7-10 days
500 µg	$1,900	7-10 days	7-10 days
1 mg	$2,730	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:Greater than 95% as determined by reducing SDS-PAGE.

Appearance:Lyophilized powder

Color:White

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COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Thioredoxin-Dependent Peroxide Reductase Mitochondrial (PRDX3) is an enzyme that belongs to the AhpC/TSA family. Human and mouse PRDX3 genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Human PRDX3 protein has an antioxidant function and is localized in the mitochondrion. PRDX3 is involved in redox regulation of the cell. PRDX3 protects radical-sensitive enzymes from oxidative damage by a radical-generating system. It acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.
Species	Human
Expression System	E. coli
Tag	Tag Free
Accession Number	P30048
Amino Acid	Pro63-Gln256
Construction	Pro63-Gln256
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, pH 8.0.
Synonyms	Thioredoxin-Dependent Peroxide Reductase Mitochondrial, Prx-III, Protein MER5 homolog, PRDX3, Peroxiredoxin-3, Peroxiredoxin III, HBC189, AOP-1, AOP1, Antioxidant Protein 1
Research Background	Thioredoxin-Dependent Peroxide Reductase Mitochondrial (PRDX3) is an enzyme that belongs to the AhpC/TSA family. Human and mouse PRDX3 genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Human PRDX3 protein has an antioxidant function and is localized in the mitochondrion. PRDX3 is involved in redox regulation of the cell. PRDX3 protects radical-sensitive enzymes from oxidative damage by a radical-generating system. It acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.

Chemical Properties

Molecular Weight

25 KDa (reducing condition)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.