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IL-1RAP/IL-1RAcP Protein, Human, Recombinant (hFc)
(Synonyms: interleukin 1 receptor accessory protein, IL-1RAcP, IL1R3, C3orf13) Copy Product InfoSynonyms: interleukin 1 receptor accessory protein, IL-1RAcP, IL1R3, C3orf13
Catalog No. TMPY-05392 Copy Product Info
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.8 kDa and the accession number is Q9NPH3-1.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $48 | 7-10 days | 7-10 days | |
| 10 µg | $79 | 7-10 days | 7-10 days | |
| 20 µg | $129 | 7-10 days | 7-10 days | |
| 50 µg | $250 | 7-10 days | 7-10 days | |
| 100 µg | $483 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Information
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized Human IL-1R3, hFc Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-IL-1R3 Antibody, hFc Tag with the EC50 of 19.2 ng/ml determined by ELISA. |
| Description | IL-1RAP/IL-1RAcP Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.8 kDa and the accession number is Q9NPH3-1. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-hFc |
| Accession Number | Q9NPH3-1 |
| Construction | Ser21-Glu359 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | interleukin 1 receptor accessory protein, IL-1RAcP, IL1R3, C3orf13 |
| Research Background | IL-1 Receptor Accessory Protein (IL-1 RAcP), also known as IL-1 R3, is a ubiquitously expressed 70-90 kDa member of the Interleukin-1 receptor family of proteins. It serves as a non-ligand-binding component of the receptors for IL-1 alpha, IL-1 beta, IL-33, and IL-36. IL-1 R3 is a coreceptor for IL1RL2 in the IL-36 signaling system. IL-1 R3 is a coreceptor with IL1R1 in the IL-1 signaling system. Associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways. |
| Molecular Weight | 65.8 kDa (Predicted); 75-85 kDa (Due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: IL-1RAP/IL-1RAcP Protein, Human, Recombinant (hFc) chemical structure | IL-1RAP/IL-1RAcP Protein, Human, Recombinant (hFc) molecular weight
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