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Anti-SFPQ Antibody (1W928) (Synonyms: Splicing factor proline/glutamine rich (polypyrimidine tract binding prote...)

Catalog No. TMAC-03719 Copy Product Info
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Anti-SFPQ Antibody (1W928) is a Rabbit antibody targeting SFPQ. Anti-SFPQ Antibody (1W928) can be used in ICC,IF,IHC,WB.

Anti-SFPQ Antibody (1W928)

Copy Product Info
🥰Excellent
Catalog No. TMAC-03719
Synonyms Splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated), Splicing factor proline/glutamine rich, Splicing factor proline and glutamine rich, Splicing factor, SFPQ_HUMAN, Sfpq, PTB-associated-splicing factor, PTB associated splicing factor, PSF, Protein phosphatase 1 regulatory subunit 140, proline- and glutamine-rich, PPP1R140, POMP100, Polypyrimidine tract-binding protein-associated-splicing factor, Polypyrimidine tract binding protein associated splicing factor, hPOMp100, DNA-binding p52/p100 complex, DNA binding p52/p100 complex 100 kDa subunit, 100 kDa subunit, 100 kDa DNA-pairing protein, 100 kDa DNA pairing protein

Anti-SFPQ Antibody (1W928) is a Rabbit antibody targeting SFPQ. Anti-SFPQ Antibody (1W928) can be used in ICC,IF,IHC,WB.

Anti-SFPQ Antibody
(1W928)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-SFPQ Antibody (1W928) is a Rabbit antibody targeting SFPQ. Anti-SFPQ Antibody (1W928) can be used in ICC,IF,IHC,WB.
SynonymsSplicing factor proline/glutamine rich (polypyrimidine tract binding protein associated), Splicing factor proline/glutamine rich, Splicing factor proline and glutamine rich, Splicing factor, SFPQ_HUMAN, Sfpq, PTB-associated-splicing factor, PTB associated splicing factor, PSF, Protein phosphatase 1 regulatory subunit 140, proline- and glutamine-rich, PPP1R140, POMP100, Polypyrimidine tract-binding protein-associated-splicing factor, Polypyrimidine tract binding protein associated splicing factor, hPOMp100, DNA-binding p52/p100 complex, DNA binding p52/p100 complex 100 kDa subunit, 100 kDa subunit, 100 kDa DNA-pairing protein, 100 kDa DNA pairing protein
Ig Type
IgG
Clone
1W928
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of SFPQ on different lysates using anti-SFPQ antibody at 1/1,000 dilution. Positive control: Lane 1: K562, Lane 2: Daudi, Lane 3: Mouse testis, Lane 4: Mouse lung.
2. Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-SFPQ antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-SFPQ antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-SFPQ antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-SFPQ antibody. Counter stained with hematoxylin.
6. Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-SFPQ antibody. Counter stained with hematoxylin.
verifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-2000; IHC: 1:50-200; ICC: 1:10-50
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundDNA- and RNA binding protein, involved in several nuclear processes. Essential pre-mRNA splicing factor required early in spliceosome formation and for splicing catalytic step II, probably as a heteromer with NONO. Binds to pre-mRNA in spliceosome C complex, and specifically binds to intronic polypyrimidine tracts. Involved in regulation of signal-induced alternative splicing. Interacts with U5 snRNA, probably by binding to a purine-rich sequence located on the 3' side of U5 snRNA stem 1b. May be involved in a pre-mRNA coupled splicing and polyadenylation process as component of a snRNP-free complex with SNRPA/U1A. The SFPQ-NONO heteromer associated with MATR3 may play a role in nuclear retention of defective RNAs. SFPQ may be involved in homologous DNA pairing; in vitro, promotes the invasion of ssDNA between a duplex DNA and produces a D-loop formation.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 100 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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