Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Dynapyrazole A is a specific inhibitor of microtubule dynamin with IC50s of 2.3 and 2.6 μM for dynein 1 and dynein 2-dependent microtubule gliding. Dynapyrazole A inhibits Hedgehog signaling with an IC50 of 1.9 μM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 31.00 | |
5 mg | In stock | $ 72.00 | |
10 mg | In stock | $ 122.00 | |
25 mg | In stock | $ 259.00 | |
50 mg | In stock | $ 443.00 | |
100 mg | In stock | $ 656.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 77.00 |
Description | Dynapyrazole A is a specific inhibitor of microtubule dynamin with IC50s of 2.3 and 2.6 μM for dynein 1 and dynein 2-dependent microtubule gliding. Dynapyrazole A inhibits Hedgehog signaling with an IC50 of 1.9 μM. |
In vitro | Dynapyrazole A displays reversible inhibition of retrograde and anterograde intraflagellar transport in Chlamydomonas. In MA-104 cells infected with the RVA-NMTL virus, Dynapyrazole A (1-3 μg/mL) dose-dependently reduces viral titers with an EC50 of 0.73 μg/mL[1]. |
Molecular Weight | 486.69 |
Formula | C20H12ClIN4O |
CAS No. | 2226517-75-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 22.5 mg/mL (46.2 mM), Sonication and heating to 60℃ are recommended.
You can also refer to dose conversion for different animals. More
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Dynapyrazole A 2226517-75-3 Cytoskeletal Signaling Dynamin inhibitor inhibit