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4-Nonylphenol polyethoxylate

🥰Excellent
Catalog No. T0824Cas No. 26027-38-3
Alias Nonoxynol, Nonoxinol-9

4-Nonylphenol polyethoxylate (Nonoxinol-9) is a typical surfactant used as a vaginal spermicide. Spermicides are locally acting non-hormonal contraceptives. When present in the vagina during intercourse, they immobilize/inactivate/damage and/or kill sperms without eliciting systemic effects. 4-Nonylphenol polyethoxylate has been in use for more than 30 years as an over-the-counter (OTC) drug in creams, gels, foams and condom lubricants. It is the most commonly used spermicidal contraceptive in the UK and the USA. In several European countries, spermicides are no longer on the market.

4-Nonylphenol polyethoxylate

4-Nonylphenol polyethoxylate

🥰Excellent
Catalog No. T0824Alias Nonoxynol, Nonoxinol-9Cas No. 26027-38-3
4-Nonylphenol polyethoxylate (Nonoxinol-9) is a typical surfactant used as a vaginal spermicide. Spermicides are locally acting non-hormonal contraceptives. When present in the vagina during intercourse, they immobilize/inactivate/damage and/or kill sperms without eliciting systemic effects. 4-Nonylphenol polyethoxylate has been in use for more than 30 years as an over-the-counter (OTC) drug in creams, gels, foams and condom lubricants. It is the most commonly used spermicidal contraceptive in the UK and the USA. In several European countries, spermicides are no longer on the market.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
500 mg$41In StockIn Stock
1 mL x 10 mM (in DMSO)$50In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
4-Nonylphenol polyethoxylate (Nonoxinol-9) is a typical surfactant used as a vaginal spermicide. Spermicides are locally acting non-hormonal contraceptives. When present in the vagina during intercourse, they immobilize/inactivate/damage and/or kill sperms without eliciting systemic effects. 4-Nonylphenol polyethoxylate has been in use for more than 30 years as an over-the-counter (OTC) drug in creams, gels, foams and condom lubricants. It is the most commonly used spermicidal contraceptive in the UK and the USA. In several European countries, spermicides are no longer on the market.
SynonymsNonoxynol, Nonoxinol-9
Chemical Properties
Molecular Weight281.44
Formula(C2H4O)nC15H24O
Cas No.26027-38-3
SmilesN.CCCCCCCCCc1ccc(OCCO)cc1
Relative Density.1.06 g/cm3. Temperature:25 °C.
ColorTransparent
AppearanceLiquid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55.00 mg/mL (195.42 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.5532 mL17.7658 mL35.5316 mL177.6578 mL
5 mM0.7106 mL3.5532 mL7.1063 mL35.5316 mL
10 mM0.3553 mL1.7766 mL3.5532 mL17.7658 mL
20 mM0.1777 mL0.8883 mL1.7766 mL8.8829 mL
50 mM0.0711 mL0.3553 mL0.7106 mL3.5532 mL
100 mM0.0355 mL0.1777 mL0.3553 mL1.7766 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
The above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.
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Keywords

Nonoxinol9Nonoxinol 9InhibitorinhibitCOX4-Nonylphenol polyethoxylate4Nonylphenol polyethoxylate4 Nonylphenol polyethoxylate
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