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(R)-(-)-1,2-Propanediol

Name: (R)-(-)-1,2-Propanediol
Brand: TargetMol
SKU: T40529
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T40529 Copy Product Info

Purity: 98%

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(R)-(-)-1,2-Propanediol is a chiral isomer of 1,2-propanediol and serves as a key chiral starting material for the synthesis of chiral drugs, fine chemicals, and functional polymers; it acts as an agonist for TRPM8 in FLIPR assays (EC50 = 2.2 μM).

(R)-(-)-1,2-Propanediol

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Catalog No. T40529

Cas No. 4254-14-2

Pack Size	Price	USA Stock	Global Stock	Quantity
5 g	$29	-	In Stock
1 mL x 10 mM (in DMSO)	$29	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:98%

Appearance:Liquid

Color:Transparent

Resource Download

COA MS HNMR

Product Introduction

Bioactivity

Description	(R)-(-)-1,2-Propanediol is a chiral isomer of 1,2-propanediol and serves as a key chiral starting material for the synthesis of chiral drugs, fine chemicals, and functional polymers; it acts as an agonist for TRPM8 in FLIPR assays (EC50 = 2.2 μM).
In vitro	(R)-(-)-1,2-Propanediol can be efficiently produced by engineered E. coli or Lactococcus lactis. In E. coli, NADH-linked glycerol dehydrogenase converts glucose/glycerol to high-purity (R)-isomers. Comparative production of (R)- and (S)-isomers across strains provides kinetic and genetic insights for industrial bio-production [1][2].

Chemical Properties

Molecular Weight	76.09
Formula	C₃H₈O₂
Cas No.	4254-14-2
Smiles	[C@H](CO)(C)O

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (1051.39 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	13.1423 mL	65.7117 mL	131.4233 mL	657.1166 mL
5 mM	2.6285 mL	13.1423 mL	26.2847 mL	131.4233 mL
10 mM	1.3142 mL	6.5712 mL	13.1423 mL	65.7117 mL
20 mM	0.6571 mL	3.2856 mL	6.5712 mL	32.8558 mL
50 mM	0.2628 mL	1.3142 mL	2.6285 mL	13.1423 mL
100 mM	0.1314 mL	0.6571 mL	1.3142 mL	6.5712 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Citations

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

1,2-Propanediol(R)()1,2Propanediol(R) ( ) 1,2 Propanediol