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DEFB4A Protein, Human, Recombinant

(Synonyms: β-Defensin 4A, β-Defensin 2, β2, Skin-Antimicrobial Peptide 1, SAP1, hBD-2, Defensin, DEFB4B, DEFB4A, DEFB4, DEFB2, DEFB102, Beta-Defensin 4A, Beta-Defensin 2, Beta 2, BD-2) Copy Product Info

Synonyms: β-Defensin 4A, β-Defensin 2, β2, Skin-Antimicrobial Peptide 1, SAP1, hBD-2, Defensin, DEFB4B, DEFB4A, DEFB4, DEFB2, DEFB102, Beta-Defensin 4A, Beta-Defensin 2, Beta 2, BD-2

Catalog No. TMPJ-00667 Copy Product Info
β-Defensin 4A is a membrane-active cationic peptide that functions in inflammation and innate immune responses. There are at least 30 β-Defensins, which are distinguished from α-Defensins by the connectivity pattern of their three intermolecular disulfide bonds. Members of the Defensin family are highly similar in protein sequence. This gene encodes Defensin, DEFB4;, which has broad-spectrum antimicrobial activity and may play an important role in innate epithelial defense. They are highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. β-Defensin 4A has low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine. The 45 amino acid mature human BD3 shares 38% and 33% amino acid sequence identity with mouse and rat BD3, respectively.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$61-In Stock
10 μg$97-In Stock
20 μg$14835 days35 days
50 μg$27235 days35 days
100 μg$48535 days35 days
200 μg$86935 days35 days
500 μg$1,90035 days35 days
1 mg$2,73035 days35 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:Greater than 95% as determined by reducing SDS-PAGE.
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
β-Defensin 4A is a membrane-active cationic peptide that functions in inflammation and innate immune responses. There are at least 30 β-Defensins, which are distinguished from α-Defensins by the connectivity pattern of their three intermolecular disulfide bonds. Members of the Defensin family are highly similar in protein sequence. This gene encodes Defensin, DEFB4;, which has broad-spectrum antimicrobial activity and may play an important role in innate epithelial defense. They are highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. β-Defensin 4A has low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine. The 45 amino acid mature human BD3 shares 38% and 33% amino acid sequence identity with mouse and rat BD3, respectively.
Species
Human
Expression System
E. coli
TagTag Free
Accession NumberO15263
Amino AcidGly24-Pro64
ConstructionGly24-Pro64
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Synonymsβ-Defensin 4A, β-Defensin 2, β2, Skin-Antimicrobial Peptide 1, SAP1, hBD-2, Defensin, DEFB4B, DEFB4A, DEFB4, DEFB2, DEFB102, Beta-Defensin 4A, Beta-Defensin 2, Beta 2, BD-2
Research Background
Chemical Properties
Molecular Weight9 KDa (reducing condition)
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Keywords

Related Tags: DEFB4A Protein, Human, Recombinant chemical structure | DEFB4A Protein, Human, Recombinant molecular weight