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Anti-P2RX7 Polyclonal Antibody
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Catalog No. TMAB-01314
Alias Purinergic receptor, P2Z receptor, P2X7, P2X purinoceptor 7, P2RX7, ATP receptor
Anti-P2RX7 Polyclonal Antibody is a Rabbit antibody targeting P2RX7. Anti-P2RX7 Polyclonal Antibody can be used in WB.
Anti-P2RX7 Polyclonal Antibody
Anti-P2RX7 Polyclonal Antibody
😃Good
Catalog No. TMAB-01314Alias Purinergic receptor, P2Z receptor, P2X7, P2X purinoceptor 7, P2RX7, ATP receptor
Anti-P2RX7 Polyclonal Antibody is a Rabbit antibody targeting P2RX7. Anti-P2RX7 Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $221 | 7-10 days | |
| 100 μL | $372 | 7-10 days | |
| 200 μL | $529 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-P2RX7 Polyclonal Antibody is a Rabbit antibody targeting P2RX7. Anti-P2RX7 Polyclonal Antibody can be used in WB. |
| Synonyms | Purinergic receptor, P2Z receptor, P2X7, P2X purinoceptor 7, P2RX7, ATP receptor |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat) |
| Verified Activity | Sample: Lane 1: Human U937 cell lysates Lane 2: Human U251 cell lysates Lane 3: Human SH-SY5Y cell lysates Primary: Anti-P2RX7 (TMAB-01314) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 69 kDa Observed band size: 74 kDa  |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The seven P2X receptors, P2X1-P2X7, form either homomeric or heteromeric channels or both. They are characterized by intracellular amino- and carboxy-termini. P2X receptors are expressed in a wide variety of tissues, including neurons, prostate, bladder, pancreas, colon, testis and ovary. The major function of the P2X receptors is to mediate synaptic transmissions between neurons and to other tissues via the binding of extracellular ATP, which acts as a neurotransmitter. The P2X receptors may be involved in the onset of necrosis or apoptosis after prolonged exposure to high concentrations of extracellular ATP. |
| Immunogen | KLH conjugated synthetic peptide: human P2RX7 |
| Antigen Species | Human |
| Gene Name | P2RX7 |
| Gene ID | |
| Protein Name | P2X purinoceptor 7 |
| Uniprot ID | |
| Biology Area | P2X Receptors |
| Function | The product P2RX7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. |
| Molecular Weight | Theoretical: 69 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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