Shopping Cart
- Remove All
Your shopping cart is currently empty
Anti-PARP1 Antibody (5J827)
😃Good
Catalog No. TMAB-01333
Alias PPOL, poly (ADP-ribose) polymerase 1, PARP-1, PARP, pADPRT-1, ARTD1, ADPRT1, ADPRT
Anti-PARP1 Antibody (5J827) is a Rabbit antibody targeting PARP1. Anti-PARP1 Antibody (5J827) can be used in FCM,WB.
Anti-PARP1 Antibody (5J827)
Anti-PARP1 Antibody (5J827)
😃Good
Catalog No. TMAB-01333Alias PPOL, poly (ADP-ribose) polymerase 1, PARP-1, PARP, pADPRT-1, ARTD1, ADPRT1, ADPRT
Anti-PARP1 Antibody (5J827) is a Rabbit antibody targeting PARP1. Anti-PARP1 Antibody (5J827) can be used in FCM,WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 μL | $154 | 7-10 days | |
| 50 μL | $272 | 7-10 days | |
| 100 μL | $488 | 7-10 days |
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View MoreResource Download
Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-PARP1 Antibody (5J827) is a Rabbit antibody targeting PARP1. Anti-PARP1 Antibody (5J827) can be used in FCM,WB. |
| Synonyms | PPOL, poly (ADP-ribose) polymerase 1, PARP-1, PARP, pADPRT-1, ARTD1, ADPRT1, ADPRT |
| Ig Type | IgG |
| Clone | 5J827 |
| Reactivity | Human |
| Verified Activity | 25 μg total protein per Lane of various lysates probed with Cleaved PARP monoclonal antibody, unconjugated (TMAB-01333) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min. |
| Application | |
| Recommended Dose | WB: 1:500-2000; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Mitochondrion outer membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.Nucleus. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]. |
| Immunogen | A synthesized peptide: human PARP 1 |
| Antigen Species | Human |
| Gene Name | PARP1 |
| Gene ID | |
| Protein Name | Poly [ADP-ribose] polymerase 1 |
| Uniprot ID | |
| Biology Area | ADP-ribosylation,Base Excision Repair,DNA Damage Recognition |
| Function | Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. Mediates the poly(ADP-ribosyl)ation of APLF and CHFR. Positively regulates the transcription of MTUS1 and negatively regulates the transcription of MTUS2/TIP150. With EEF1A1 and TXK, forms a complex that acts as a T-helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production. |
| Molecular Weight | Theoretical: 89/116 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Calculator
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Sci Citations
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Anti-PARP1 Antibody (5J827) | purchase Anti-PARP1 Antibody (5J827) | Anti-PARP1 Antibody (5J827) cost | order Anti-PARP1 Antibody (5J827) | Anti-PARP1 Antibody (5J827) molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.