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DMPQ dihydrochloride

Name: DMPQ dihydrochloride
Brand: TargetMol
SKU: T22740
Price: 59 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T22740Cas No. 1123491-15-5

DMPQ dihydrochloride is a selective inhibitor of human vascular PDGFRβ (platelet-derived growth factor receptor β), with an IC50 of 80 nM, and can be used for research on cardiovascular diseases.

DMPQ dihydrochloride

🥰Excellent

Purity: 99.51%

Catalog No. T22740Cas No. 1123491-15-5

DMPQ dihydrochloride is a selective inhibitor of human vascular PDGFRβ (platelet-derived growth factor receptor β), with an IC50 of 80 nM, and can be used for research on cardiovascular diseases.

Pack Size	Price	Availability
1 mg	$59	In Stock
5 mg	$142	In Stock
10 mg	$208	In Stock
25 mg	$356	In Stock
50 mg	$527	In Stock

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Purity:99.51%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description

DMPQ dihydrochloride is a selective inhibitor of human vascular PDGFRβ (platelet-derived growth factor receptor β), with an IC50 of 80 nM, and can be used for research on cardiovascular diseases.

Chemical Properties

Molecular Weight	339.22
Formula	C₁₆H₁₆Cl₂N₂O₂
Cas No.	1123491-15-5
Smiles	COC1=CC(OC)=C2C(N=CC(C3=CC=NC=C3)=C2)=C1.Cl.Cl
Relative Density.	no data available

Storage & Solubility Information

Storage

keep away from moisture | store at 4°C | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 80 mg/mL (235.84 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	2.9479 mL	14.7397 mL	29.4794 mL	147.3970 mL
5 mM	0.5896 mL	2.9479 mL	5.8959 mL	29.4794 mL
10 mM	0.2948 mL	1.4740 mL	2.9479 mL	14.7397 mL
20 mM	0.1474 mL	0.7370 mL	1.4740 mL	7.3698 mL
50 mM	0.0590 mL	0.2948 mL	0.5896 mL	2.9479 mL
100 mM	0.0295 mL	0.1474 mL	0.2948 mL	1.4740 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc