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Cys-Pexiganan TFA

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Catalog No. T83717

Cys-pexiganan, a derivative of pexiganan with an added N-terminal cysteine, is an antimicrobial peptide effective against P. aeruginosa and S. aureus, with minimum inhibitory concentrations (MICs) of 64 and 16 µg/ml, respectively. Its conjugation to cellulose acetate-incorporated polyvinyl alcohol electrospun mats enhances the clotting of isolated recalcified human plasma.

Cys-Pexiganan TFA

Cys-Pexiganan TFA

😃Good
Catalog No. T83717
Cys-pexiganan, a derivative of pexiganan with an added N-terminal cysteine, is an antimicrobial peptide effective against P. aeruginosa and S. aureus, with minimum inhibitory concentrations (MICs) of 64 and 16 µg/ml, respectively. Its conjugation to cellulose acetate-incorporated polyvinyl alcohol electrospun mats enhances the clotting of isolated recalcified human plasma.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$68InquiryInquiry
5 mg$297InquiryInquiry
10 mg$550InquiryInquiry
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Cys-pexiganan, a derivative of pexiganan with an added N-terminal cysteine, is an antimicrobial peptide effective against P. aeruginosa and S. aureus, with minimum inhibitory concentrations (MICs) of 64 and 16 µg/ml, respectively. Its conjugation to cellulose acetate-incorporated polyvinyl alcohol electrospun mats enhances the clotting of isolated recalcified human plasma.
Chemical Properties
Molecular Weight2580.30
FormulaC125H215N33O23S.XCF3COOH
SmilesO=C([C@@H](N)CS)NCC(N[C@@]([H])([C@H](CC)C)C(NCC(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@H](C(N[C@@H](C)C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(NCC(N[C@H](C(N[C@@H](C)C(N[C@@H](CC3=CC=CC=C3)C(N[C@H](C(N[C@H](C(N[C@@]([H])([C@H](CC)C)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@H](C(N)=O)CCCCN)=O)CCCCN)=O)=O)=O)CCCCN)=O)C(C)C)=O)=O)=O)CCCCN)=O)=O)=O)CCCCN)=O)CCCCN)=O)=O)CCCCN)=O)CCCCN)=O)=O)=O)CCCCN)=O)=O)=O.OC(C(F)(F)F)=O
SequenceCys-Gly-Ile-Gly-Lys-Phe-Leu-Lys-Lys-Ala-Lys-Lys-Phe-Gly-Lys-Ala-Phe-Val-Lys-Ile-Leu-Lys-Lys-NH2
Sequence ShortCGIGKFLKKAKKFGKAFVKILKK-NH2
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: soluble

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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