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CAY10761 is an inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1; IC50s = 467 and 429 μM for the human and snake venom enzymes, respectively).1,2 It also inhibits mushroom tyrosinase (Ki = 1.9 μM) and urease from jack bean, P. mirabilis, and B. pasteurii (IC50s = 0.093, <0.125, and 0.089 mM, respectively, at pH 8.2).3,4
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | TBD | 35 days | |
5 mg | TBD | 35 days | |
10 mg | TBD | 35 days | |
25 mg | TBD | 35 days |
Description | CAY10761 is an inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1; IC50s = 467 and 429 μM for the human and snake venom enzymes, respectively).1,2 It also inhibits mushroom tyrosinase (Ki = 1.9 μM) and urease from jack bean, P. mirabilis, and B. pasteurii (IC50s = 0.093, <0.125, and 0.089 mM, respectively, at pH 8.2).3,4 |
Alias | CAY10761 |
Molecular Weight | 244.29 |
Formula | C7H8N4O2S2 |
Cas No. | 333409-31-7 |
Relative Density. | 1.77 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Solubility Information | DMF: 30 mg/mL (122.8 mM), Sonication is recommended. DMSO: 30 mg/mL (122.8 mM), Sonication is recommended. DMSO:PBS (pH 7.2) (1:4): 0.2 mg/mL (0.82 mM), Sonication is recommended. |
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