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Prostaglandin G/H synthase 1 inhibitor

🥰Excellent
Catalog No. T27066Cas No. 4943-86-6
Alias CP74006, CP 74006, 2-Amino-N-(4-chlorophenyl)benzamide

Prostaglandin G/H synthase 1 inhibitor (CP 74006) is a selective D5D inhibitor with an IC(50) value of 20 nM.

Prostaglandin G/H synthase 1 inhibitor

Prostaglandin G/H synthase 1 inhibitor

🥰Excellent
Purity: 99.76%
Catalog No. T27066Alias CP74006, CP 74006, 2-Amino-N-(4-chlorophenyl)benzamideCas No. 4943-86-6
Prostaglandin G/H synthase 1 inhibitor (CP 74006) is a selective D5D inhibitor with an IC(50) value of 20 nM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
200 mg$39-In Stock
500 mg$65-In Stock
1 g$96-In Stock
2 g$138-In Stock
1 mL x 10 mM (in DMSO)$29-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.76%
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Product Introduction

Bioactivity
Description
Prostaglandin G/H synthase 1 inhibitor (CP 74006) is a selective D5D inhibitor with an IC(50) value of 20 nM.
In vitro
Prostaglandin G/H synthase 1 inhibitor inhibits D5D in the rat liver microsomal assay with IC50 of 0.04 μM[2].
SynonymsCP74006, CP 74006, 2-Amino-N-(4-chlorophenyl)benzamide
Chemical Properties
Molecular Weight246.69
FormulaC13H11ClN2O
Cas No.4943-86-6
SmilesNC1=C(C=CC=C1)C(=O)NC1=CC=C(Cl)C=C1
Relative Density.1.351g/cm3
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (202.68 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.0537 mL20.2684 mL40.5367 mL202.6835 mL
5 mM0.8107 mL4.0537 mL8.1073 mL40.5367 mL
10 mM0.4054 mL2.0268 mL4.0537 mL20.2684 mL
20 mM0.2027 mL1.0134 mL2.0268 mL10.1342 mL
50 mM0.0811 mL0.4054 mL0.8107 mL4.0537 mL
100 mM0.0405 mL0.2027 mL0.4054 mL2.0268 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Prostaglandin G/H synthase 1 inhibitorFatty acid desaturase Δ5DCP-74006
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