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Sunitinib Process Impurity 1

😃Good
Catalog No. T9421Cas No. 452105-33-8

5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid is a sunitinib impurity.

Sunitinib Process Impurity 1

Sunitinib Process Impurity 1

😃Good
Purity: 98.79%
Catalog No. T9421Cas No. 452105-33-8
5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid is a sunitinib impurity.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$36-In Stock
50 mg$60-In Stock
100 mg$98-In Stock
1 mL x 10 mM (in DMSO)$39-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:98.79%
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Product Introduction

Bioactivity
Description
5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid is a sunitinib impurity.
Chemical Properties
Molecular Weight300.28
FormulaC16H13FN2O3
Cas No.452105-33-8
SmilesC(=C1C=2C(NC1=O)=CC=C(F)C2)C3=C(C)C(C(O)=O)=C(C)N3
Relative Density.1.454 g/cm3 (Predicted)
ColorOrange
AppearanceSolid
Storage & Solubility Information
Storagestore at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (183.16 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3302 mL16.6511 mL33.3023 mL166.5113 mL
5 mM0.6660 mL3.3302 mL6.6605 mL33.3023 mL
10 mM0.3330 mL1.6651 mL3.3302 mL16.6511 mL
20 mM0.1665 mL0.8326 mL1.6651 mL8.3256 mL
50 mM0.0666 mL0.3330 mL0.6660 mL3.3302 mL
100 mM0.0333 mL0.1665 mL0.3330 mL1.6651 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

5(5Fluoro2oxo1,2dihydroindol3ylidenemethyl)2,4dimethyl1Hpyrrole3carboxylic Acid5 (5 Fluoro 2 oxo 1,2 dihydro indol 3 ylidenemethyl) 2,4 dimethyl 1H pyrrole 3 carboxylic Acid
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