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Sunitinib Process Impurity 1

Name: Sunitinib Process Impurity 1
Brand: TargetMol
SKU: T9421
Price: 36 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T9421Cas No. 452105-33-8

5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid is a sunitinib impurity.

Sunitinib Process Impurity 1

😃Good

Purity: 98.79%

Catalog No. T9421Cas No. 452105-33-8

5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid is a sunitinib impurity.

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$36	-	In Stock
50 mg	$60	-	In Stock
100 mg	$98	-	In Stock
1 mL x 10 mM (in DMSO)	$39	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:98.79%

Appearance:Solid

Color:Orange

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid is a sunitinib impurity.

Chemical Properties

Molecular Weight	300.28
Formula	C₁₆H₁₃FN₂O₃
Cas No.	452105-33-8
Smiles	C(=C1C=2C(NC1=O)=CC=C(F)C2)C3=C(C)C(C(O)=O)=C(C)N3
Relative Density.	1.454 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (183.16 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3302 mL	16.6511 mL	33.3023 mL	166.5113 mL
5 mM	0.6660 mL	3.3302 mL	6.6605 mL	33.3023 mL
10 mM	0.3330 mL	1.6651 mL	3.3302 mL	16.6511 mL
20 mM	0.1665 mL	0.8326 mL	1.6651 mL	8.3256 mL
50 mM	0.0666 mL	0.3330 mL	0.6660 mL	3.3302 mL
100 mM	0.0333 mL	0.1665 mL	0.3330 mL	1.6651 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

5(5Fluoro2oxo1,2dihydroindol3ylidenemethyl)2,4dimethyl1Hpyrrole3carboxylic Acid5 (5 Fluoro 2 oxo 1,2 dihydro indol 3 ylidenemethyl) 2,4 dimethyl 1H pyrrole 3 carboxylic Acid