Shopping Cart
- Remove All
- Your shopping cart is currently empty
Anti-IL-6R Antibody-APC (6K916) is a APC-conjugated Rabbit antibody targeting IL-6R. Anti-IL-6R Antibody-APC (6K916) can be used in FCM.
Description | Anti-IL-6R Antibody-APC (6K916) is a APC-conjugated Rabbit antibody targeting IL-6R. Anti-IL-6R Antibody-APC (6K916) can be used in FCM. |
Ig Type | Monoclonal Rabbit IgG |
Clone | 6K916 |
Reactivity | Human |
Verified Activity | Flow cytometric analysis of Human IL-6R expression on U266 cells. Cells were stained with APC-conjugated anti-Human IL-6R. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
Application | FCM |
Recommended Dose | 5 μl/Test, 0.1 mg/ml |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human IL-6R (rh IL-6R; TMPY-00864; NP_000556.1; Met1-Pro365), and conjugated with APC under optimum conditions, the unreacted APC was removed. |
Purification | Protein A |
Appearance | Liquid |
Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
Research Background | Interleukin 6 receptor (IL-6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor. The low concentration of a soluble form of IL-6 receptor (SIL-6R) acts as an agonist of IL-6 activity. In the IL-6R/CD126/IL6R system, both a membrane-bound IL-6R and a SIL-6R protein can mediate IL-6 signals into the cells through the interaction of gp130. The resulting IL-6/sIL-6R protein complex is also capable of binding to gp130 and inducing intracellular signaling. Through this so-called 'trans-signaling' mechanism, IL-6 can stimulate cells that lack an endogenous mIL-6R. High levels of IL-6 and SIL-6R have been reported in several chronic inflammatory and autoimmune diseases as well as in cancer.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
Conjucates | APC |
Others Formats | Unconjugated/FITC/PE |
Antibody Types Available | 4 |
Immunogen | Recombinant Human IL-6R Protein (TMPY-00864) |
Antigen Species | Human |
Biology Area | Neuroinflammation |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
Transport | Shipping with blue ice. |
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.