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GM-CSF/CSF2 Protein, Human, Recombinant (E. coli)

Catalog No. TMPJ-01465
Synonyms: Colony-Stimulating Factor, CSF2, CSF, Sargramostim, Molgramostin, Granulocyte-Macrophage Colony-Stimulating Factor, GMCSF, GM-CSF

Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic, monocytes/ macrophages and eosinophils. GM-CSF has a functional role on non-hematopoitic cells. It can induce human endothelial cells to migrate and proliferate. Additionally, GM-CSF can also stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma and adenocarcinoma cell lines.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
GM-CSF/CSF2 Protein, Human, Recombinant (E. coli)
Pack Size Availability Price/USD Quantity
10 μg In stock $ 92.00
20 μg 5 days $ 148.00
50 μg 5 days $ 278.00
100 μg 5 days $ 408.00
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Biological Description
Technical Params
Product Properties
Biological Information Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells.The ED50 for this effect is 4-20 pg/ml. (QC verified)

Description Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic, monocytes/ macrophages and eosinophils. GM-CSF has a functional role on non-hematopoitic cells. It can induce human endothelial cells to migrate and proliferate. Additionally, GM-CSF can also stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma and adenocarcinoma cell lines.
Species Human
Expression System E.coli
Tag Tag Free
Accession Number P04141
Synonyms Colony-Stimulating Factor, CSF2, CSF, Sargramostim, Molgramostin, Granulocyte-Macrophage Colony-Stimulating Factor, GMCSF, GM-CSF
Amino Acid Ala18-Glu144
Construction Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor is produced by our E.coli expression system and the target gene encoding Ala18-Glu144 is expressed.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. Greater than 95% as determined by SEC-HPLC.

Endotoxin Less than 0.001 ng/µg (0.01 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Research Background Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic, monocytes/ macrophages and eosinophils. GM-CSF has a functional role on non-hematopoitic cells. It can induce human endothelial cells to migrate and proliferate. Additionally, GM-CSF can also stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma and adenocarcinoma cell lines.

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Keywords

GM-CSF/CSF2 Protein, Human, Recombinant (E. coli) Colony-Stimulating Factor CSF2 CSF Sargramostim Molgramostin Granulocyte-Macrophage Colony-Stimulating Factor CSF 2 GMCSF CSF-2 GM-CSF recombinant recombinant-proteins proteins protein

 

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