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Anti-Retinoid X Receptor alpha Antibody (8D993)

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Catalog No. TMAC-03587

Anti-Retinoid X Receptor alpha Antibody (8D993) is a Rabbit antibody targeting Retinoid X Receptor alpha. Anti-Retinoid X Receptor alpha Antibody (8D993) can be used in WB,ICC,IF,IHC,IP.

Anti-Retinoid X Receptor alpha Antibody (8D993)

Anti-Retinoid X Receptor alpha Antibody (8D993)

😃Good
Catalog No. TMAC-03587
Anti-Retinoid X Receptor alpha Antibody (8D993) is a Rabbit antibody targeting Retinoid X Receptor alpha. Anti-Retinoid X Receptor alpha Antibody (8D993) can be used in WB,ICC,IF,IHC,IP.
Pack SizePriceAvailabilityQuantity
50 μL$2977-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-Retinoid X Receptor alpha Antibody (8D993) is a Rabbit antibody targeting Retinoid X Receptor alpha. Anti-Retinoid X Receptor alpha Antibody (8D993) can be used in WB,ICC,IF,IHC,IP.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:1000-5000; IHC: 1:50-200; ICC: 1:50-200; IP: 1:10-50
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundReceptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid. RXRA serves as a common heterodimeric partner for a number of nuclear receptors. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation. The RXRA/PPARA heterodimer is required for PPARA transcriptional activity on fatty acid oxidation genes such as ACOX1 and the P450 system genes.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: N-terminal human Retinoid X Receptor alpha
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 51 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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