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Darenzepine

Catalog No. T10961 Copy Product Info
Purity: 99.87%
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Darenzepine is a muscarinic receptor inhibitor.

Darenzepine

Copy Product Info
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Catalog No. T10961

Darenzepine is a muscarinic receptor inhibitor.

Darenzepine
Cas No. 84629-61-8
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$226In StockIn Stock
5 mg$449In StockIn Stock
10 mg$630In StockIn Stock
25 mg$936In StockIn Stock
50 mg$1,250In StockIn Stock
100 mg$1,690In StockIn Stock
1 mL x 10 mM (in DMSO)$497In StockIn Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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Purity:99.87%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Darenzepine is a muscarinic receptor inhibitor.
In vitro
Darenzepine can be used to treat CNS diseases[1].
Chemical Properties
Molecular Weight347.41
FormulaC21H21N3O2
Cas No.84629-61-8
SmilesC(\C(=O)N1CCN(C)CC1)=C/2\C=3C(C(=O)NC=4C2=CC=CC4)=CC=CC3
Relative Density.1.278 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 11 mg/mL (31.66 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.8784 mL14.3922 mL28.7844 mL143.9222 mL
5 mM0.5757 mL2.8784 mL5.7569 mL28.7844 mL
10 mM0.2878 mL1.4392 mL2.8784 mL14.3922 mL
20 mM0.1439 mL0.7196 mL1.4392 mL7.1961 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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