IL-13RA1 Protein, Mouse, Recombinant (His)

Name: IL-13RA1 Protein, Mouse, Recombinant (His)
Brand: TargetMol
SKU: TMPY-01170
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: NR4, interleukin 13 receptor, α1, interleukin 13 receptor, alpha 1, Il13ra, IL-13r[a], CD213a1, AI882074) Copy Product Info

Synonyms: NR4, interleukin 13 receptor, α1, interleukin 13 receptor, alpha 1, Il13ra, IL-13r[a], CD213a1, AI882074

Catalog No. TMPY-01170 Copy Product Info

Purity: 99.1%

IL-13RA1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.6 kDa and the accession number is O09030.

Pack Size	Price	USA Stock	Global Stock
10 µg	$30	-	In Stock
20 µg	$44	-	In Stock
50 µg	$79	-	In Stock
100 µg	$143	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.1%

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	1.Measured by its binding ability in a functional ELISA. 2. Immobilized mouse IL13RA1-His at 10μg/mL (100μL/well) can bind human Fc-IL13, the EC50 of human Fc-IL13 is 0.5-1.5 μg/mL.
Description	IL-13RA1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.6 kDa and the accession number is O09030.
Species	Mouse
Expression System	HEK293 Cells
Tag	C-His
Accession Number	O09030
Construction	A DNA sequence encoding the extracellular domain (Met 1-Thr 340) of mouse IL13Rα1 (NP_598751.3) precursor was fused with the a polyhistidine tag at the C-terminus. Predicted N terminal: Ala 26
Protein Purity	> 98 % as determined by SDS-PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstituted with sterile deionized water to 0.71 mg/mL. Reconstitution conditions may vary depending on the lot.
Synonyms	NR4, interleukin 13 receptor, α1, interleukin 13 receptor, alpha 1, Il13ra, IL-13r[a], CD213a1, AI882074
Research Background	Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. IL13RA1/IL-13RA1 serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2 and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3, and STAT6 induced by IL13 and IL4. IL13RA1/IL-13RA1 binds with low affinity to interleukin-13 (IL13). This subunit together with IL4RA can form a functional receptor for IL13. IL13RA1/IL-13RA1 also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.

Chemical Properties

Molecular Weight

37.6 kDa (predicted); 50-55 kDa (reducing condition, due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.