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TargetMol | Compound Library

Human Endogenous Metabolite Library

Catalog No. L2500

Human endogenous metabolites, which are produced and found within the human body, primarily include carbohydrates, bioactive peptides, nucleosides and nucleic acids, endogenous regulatory factors, cytokines, and proteins. These metabolites are often involved in essential physiological processes in the body, exerting specific physiological functions and biological activities.
Human endogenous metabolites can serve as diagnostic biomarkers. For instance, in the field of cancer research, methods for malignant tumors diagnose, drug screening, and drug toxicity assessment based on the abnormal changes in characteristic small-molecule metabolic biomarkers inside and outside tumor cells have become a hotspot for research. In addition to their role as biomarkers, human endogenous metabolites also play crucial physiological roles. Numerous research results confirms that there is a close relationship between many diseases and the alterations in endogenous substances. Therefore, investigating endogenously active compounds as a starting point for finding drugs to treat diseases has become one of the primary approaches in drug research.
The TargetMol's Human Endogenous Metabolite Library consists of a selection of 603 human endogenous metabolites, serving as effective tools for exploring the disease mechanisms and discovering new drugs.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L2500

Human Endogenous Metabolite Library

size

  • 1 mg
  • 10 µL x 10 mM (in DMSO)
  • 30 µL x 10 mM (in DMSO)
  • 50 µL x 10 mM (in DMSO)
  • 100 µL x 10 mM (in DMSO)
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Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Product Description Product Description

  • A collection of 603 selected human endogenous metabolites for high throughput and high content screening.
  • Some products are already approved or in clinical phase, indicating both biological safety and significant biological activity.
  • Diverse categories, including carboxylic acids, amino acids, biogenic amines, polyamines, nucleotides, coenzymes, vitamins, carbohydrates, fatty acids, lipids, steroids, hormones and various other metabolism-related compounds.
  • Detailed information, including molecular formula, molecular weight, SMILES, product descriptions, compound categories, cellular distribution, biological sample distribution, tissue distribution, related diseases, and references.
  • Utilization of various detection techniques such as NMR, HPLC, and LCMS to ensure accurate compound structures and high purity, and reduces false positives.
  • Provide professional plate map design: Ensure that each row and column contains compounds with distinct molecular weights to facilitate multiplexing in mass spectrometry.

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Endogenous Metabolite
Apoptosis
Antibacterial
Nucleoside Antimetabolite/Analog
Autophagy
DNA/RNA Synthesis
ROS
NF-κB
Antioxidant
Amino Acids and Derivatives
iGluR
Estrogen/progestogen Receptor
Dehydrogenase
Caspase
Drug Metabolite
Mitochondrial Metabolism
Liposome
Ferroptosis
ERK
Reactive Oxygen Species
NO Synthase
GluR
Interleukin
Akt
Nrf2
GABA Receptor
Antifungal
Estrogen Receptor/ERR
PPAR
Glucocorticoid Receptor
NMDAR
Adenosine Receptor
Virus Protease
Parasite
Influenza Virus
5-HT Receptor
TNF
Potassium Channel
ATPase
Chloride channel
Glutathione Peroxidase
Phosphatase
PARP
FXR
Calcium Channel
TRP/TRPV Channel
Adrenergic Receptor
Fatty Acid Synthase
HSV
MMP
Dopamine Receptor
Src
p38 MAPK
Arginase
P2Y Receptor
NADPH
Cysteine Protease
Aryl Hydrocarbon Receptor
GlyT
Opioid Receptor
Cytochromes P450
COX
mTOR
GPCR19
Cannabinoid Receptor
AChR
HMG-CoA Reductase
Tyrosinase
Antibiotic
NOD-like Receptor (NLR)
Thyroid hormone receptor(THR)
GPCR
HIV Protease
ROR
PI3K
Reductase
Histone Demethylase
Histamine Receptor
Mitophagy
Progesterone Receptor
Serine Protease
Liver X Receptor
PKC
Amylase
IL Receptor
Cholinesterase (ChE)
HCAR
glycosidase
Androgen Receptor
TLR
Bcl-2 Family
STAT
AMPK
Phospholipase
NOD
Ras
AhR
Imidazoline Receptor
Vitamin
NOS
CAT
Carbonic Anhydrase
Transferase
DHFR
YAP
c-Met/HGFR
JNK
Melatonin Receptor
Galectin
CaSR
Bcl-6
MRP
PKA
Wnt/beta-catenin
Glutaminase
MAO
LDL
Raf
MT Receptor
Antifection
Hedgehog/Smoothened
Bradykinin Receptor
CXCR
Somatostatin
PANoptosis
CaMK
TGF-beta/Smad
Lipid
OXPHOS
MAPK
Glutathione reductase
Survivin
Antiviral
HSP
Prostaglandin Receptor
Trk receptor
Free radical scavengers
Histone Acetyltransferase
CPT
Decarboxylase
cGAS
ASK
Pyroptosis
IκB/IKK
GPX
Retinoid Receptor
HDAC
Oxytocin Receptor
MDM-2/p53
Neurokinin receptor
DNA Methyltransferase
HIF/HIF Prolyl-Hydroxylase
ROS Kinase
CFTR
Glyoxalase