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TargetMol | Compound Library

Human Endogenous Metabolite Library

Catalog No. L2500

Human endogenous metabolites, which are produced and found within the human body, primarily include carbohydrates, bioactive peptides, nucleosides and nucleic acids, endogenous regulatory factors, cytokines, and proteins. These metabolites are often involved in essential physiological processes in the body, exerting specific physiological functions and biological activities.
Human endogenous metabolites can serve as diagnostic biomarkers. For instance, in the field of cancer research, methods for malignant tumors diagnose, drug screening, and drug toxicity assessment based on the abnormal changes in characteristic small-molecule metabolic biomarkers inside and outside tumor cells have become a hotspot for research. In addition to their role as biomarkers, human endogenous metabolites also play crucial physiological roles. Numerous research results confirms that there is a close relationship between many diseases and the alterations in endogenous substances. Therefore, investigating endogenously active compounds as a starting point for finding drugs to treat diseases has become one of the primary approaches in drug research.
The TargetMol's Human Endogenous Metabolite Library consists of a selection of 499 human endogenous metabolites, serving as effective tools for exploring the disease mechanisms and discovering new drugs.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L2500

Human Endogenous Metabolite Library

size

  • 1 mg
  • 10 µL x 10 mM (in DMSO)
  • 20 µL x 10 mM (in DMSO)
  • 30 µL x 10 mM (in DMSO)
  • 50 µL x 10 mM (in DMSO)
  • 100 µL x 10 mM (in DMSO)
  • 250 µL x 10 mM (in DMSO)
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Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Product Description Product Description

  • A collection of 499 selected human endogenous metabolites for high throughput and high content screening.
  • Some products are already approved or in clinical phase, indicating both biological safety and significant biological activity.
  • Diverse categories, including carboxylic acids, amino acids, biogenic amines, polyamines, nucleotides, coenzymes, vitamins, carbohydrates, fatty acids, lipids, steroids, hormones and various other metabolism-related compounds.
  • Detailed information, including molecular formula, molecular weight, SMILES, product descriptions, compound categories, cellular distribution, biological sample distribution, tissue distribution, related diseases, and references.
  • Utilization of various detection techniques such as NMR, HPLC, and LCMS to ensure accurate compound structures and high purity, and reduces false positives.
  • Provide professional plate map design: Ensure that each row and column contains compounds with distinct molecular weights to facilitate multiplexing in mass spectrometry.

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Endogenous Metabolite
Apoptosis
Antibacterial
Nucleoside Antimetabolite/Analog
Autophagy
DNA/RNA Synthesis
ROS
Amino Acids and Derivatives
iGluR
Estrogen/progestogen Receptor
Dehydrogenase
NF-κB
Caspase
Drug Metabolite
Ferroptosis
Antioxidant
ERK
GluR
Interleukin
Nrf2
NO Synthase
Estrogen Receptor/ERR
Glucocorticoid Receptor
Mitochondrial Metabolism
Reactive Oxygen Species
Akt
GABA Receptor
Antifungal
Adenosine Receptor
Phosphatase
Virus Protease
Parasite
NMDAR
5-HT Receptor
Potassium Channel
ATPase
Glutathione Peroxidase
PPAR
FXR
Adrenergic Receptor
Fatty Acid Synthase
Liposome
Dopamine Receptor
Src
p38 MAPK
Arginase
P2Y Receptor
NADPH
PARP
Cysteine Protease
Calcium Channel
TRP/TRPV Channel
Aryl Hydrocarbon Receptor
HSV
MMP
mTOR
Androgen Receptor
GPCR19
Influenza Virus
TNF
AChR
NOD
HMG-CoA Reductase
Tyrosinase
Antibiotic
NOD-like Receptor (NLR)
GPCR
Chloride channel
Reductase
Histamine Receptor
Mitophagy
Progesterone Receptor
Serine Protease
Liver X Receptor
PKC
Amylase
GlyT
IL Receptor
Cholinesterase (ChE)
glycosidase
Cytochromes P450
COX
Bcl-2 Family
STAT
AMPK
Cannabinoid Receptor
Ras
AhR
Imidazoline Receptor
Thyroid hormone receptor(THR)
HIV Protease
NOS
CAT
Carbonic Anhydrase
Transferase
DHFR
ROR
YAP
c-Met/HGFR
PI3K
JNK
Melatonin Receptor
Galectin
Bcl-6
PKA
MRP
Wnt/beta-catenin
Glutaminase
MAO
LDL
Raf
MT Receptor
Antifection
Opioid Receptor
Hedgehog/Smoothened
Bradykinin Receptor
CXCR
HCAR
Somatostatin
PANoptosis
CaMK
TGF-beta/Smad
Lipid
OXPHOS
Glutathione reductase
MAPK
Survivin
Prostaglandin Receptor
HSP
TLR
Trk receptor
Free radical scavengers
Histone Acetyltransferase
CPT
Decarboxylase
cGAS
ASK
Pyroptosis
IκB/IKK
GPX
Retinoid Receptor
Phospholipase
Oxytocin Receptor
MDM-2/p53
Neurokinin receptor
DNA Methyltransferase
ROS Kinase
Vitamin