Human Endogenous Metabolite Library

Catalog No. L2500

Library Compound List Excel SDF

Human endogenous metabolites, which are produced and found within the human body, primarily include carbohydrates, bioactive peptides, nucleosides and nucleic acids, endogenous regulatory factors, cytokines, and proteins. These metabolites are often involved in essential physiological processes in the body, exerting specific physiological functions and biological activities.

Human endogenous metabolites can serve as diagnostic biomarkers. For instance, in the field of cancer research, methods for malignant tumors diagnose, drug screening, and drug toxicity assessment based on the abnormal changes in characteristic small-molecule metabolic biomarkers inside and outside tumor cells have become a hotspot for research. In addition to their role as biomarkers, human endogenous metabolites also play crucial physiological roles. Numerous research results confirms that there is a close relationship between many diseases and the alterations in endogenous substances. Therefore, investigating endogenously active compounds as a starting point for finding drugs to treat diseases has become one of the primary approaches in drug research.

The TargetMol’s Human Endogenous Metabolite Library consists of a selection of 508 human endogenous metabolites, serving as effective tools for exploring the disease mechanisms and discovering new drugs.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Pack Size
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)

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please contact our compound library specialist for a customized compound library at inquiry@targetmol.com

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Product Description

A collection of 508 selected human endogenous metabolites for high throughput and high content screening.
Some products are already approved or in clinical phase, indicating both biological safety and significant biological activity.
Diverse categories, including carboxylic acids, amino acids, biogenic amines, polyamines, nucleotides, coenzymes, vitamins, carbohydrates, fatty acids, lipids, steroids, hormones and various other metabolism-related compounds.
Detailed information, including molecular formula, molecular weight, SMILES, product descriptions, compound categories, cellular distribution, biological sample distribution, tissue distribution, related diseases, and references.
Utilization of various detection techniques such as NMR, HPLC, and LCMS to ensure accurate compound structures and high purity, and reduces false positives.

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
Shipped with blue ice

Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (13.2 MB) Request for Library Compostion in Excel and SDF files

Publications Cited TargetMol Libraries

1. Immunity. 2023. 2. Cell Stem Cell. 2022 Apr 29(4) 545–558. 3. Science Bulletin. 2022. 4. Science Translational Medicine. 2022, 14(656): eabn3231. 5. Science Advances. 2023, 9(9): eade3760. 6. Nature. 2020, 582: 289-293. 7. Nature Biotechnology. 2021, 39(11): 1444-1452. 8. Nature Communications. 2022, 13(1): 1-15.. 9. Nature Communications. 2023, 14(1): 1020..

10. Nature Communications. 2023, 14(1): 2756.. 11. Blood. 2021, 137(11): 1478-1490. 12. Nucleic Acids Research. 2021. 13. Nature Communications. 2023, 14(1): 7574. 14. Advanced Science. 2020, 7(16): 2000925. 15. Angewandte Chemie. 2021. 16. Acta Pharmaceutica Sinica B. 2022. 17. Protein & Cell. 2021, 12(11): 877-888. 18. Bone Research. 2023, 11(1): 54. 19. Pharmacology & Therapeutics. (2021): 107930. 20. Nature Communications. 2021, 12(1): 1-12. 21. Journal of Cell Biology. 2022, 221(5): e202112024.

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Library Composition

Endogenous Metabolite (471)

Apoptosis (19)

Autophagy (18)

Antibacterial (16)

DNA/RNA Synthesis (10)

Amino Acids and Derivatives (9)

Nucleoside Antimetabolite/Analog (9)

Estrogen/progestogen Receptor (9)

Reactive Oxygen Species (9)

Ferroptosis (8)

5-HT Receptor (6)

iGluR (6)

Influenza Virus (6)

GluR (6)

NO Synthase (5)

NMDAR (5)

Antifungal (5)

Antioxidant (4)

Adenosine Receptor (4)

Estrogen Receptor/ERR (3)

FXR (3)

GABA Receptor (3)

Glucocorticoid Receptor (3)

Mitophagy (3)

Dopamine Receptor (3)

Cannabinoid Receptor (3)

Dehydrogenase (3)

Arginase (3)

AhR (3)

TNF (3)

Thyroid hormone receptor(THR) (3)

ROS (3)

Phosphatase (3)

PPAR (3)

Aryl Hydrocarbon Receptor (2)

Anti-infection (2)

Antibiotic (2)

Chloride channel (2)

ATPase (2)

AMPK (2)

Glutathione reductase (2)

GPCR19 (2)

Caspase (2)

HSV (2)

AChR (2)

Imidazoline Receptor (2)

HMG-CoA Reductase (2)

Reductase (2)

Prostaglandin Receptor (2)

Progesterone Receptor (2)

Potassium Channel (2)

PKC (2)

MMP (2)

NOD (2)

Transferase (2)

TRP/TRPV Channel (2)

Bradykinin Receptor (1)

Calcium Channel (1)

Beta Amyloid (1)

CaMK (1)

PKA (1)

PARP (1)

Carbonic Anhydrase (1)

P450 (1)

Liver X Receptor (1)

Retinoid Receptor (1)

Cysteine Protease (1)

Reverse Transcriptase (1)

Antifection (1)

ROR (1)

Somatostatin (1)

Androgen Receptor (1)

Trk receptor (1)

Akt (1)

Adrenergic Receptor (1)

Tyrosinase (1)

Virus Protease (1)

AChE (1)

p38 MAPK (1)

P2Y Receptor (1)

Decarboxylase (1)

MT Receptor (1)

MAO (1)

Melatonin Receptor (1)

IL Receptor (1)

Microtubule Associated (1)

Mitochondrial Metabolism (1)

HSP (1)

Wnt/beta-catenin (1)

HIV Protease (1)

Histamine Receptor (1)

HIF (1)

GlyT (1)

MRP (1)

Glutathione Peroxidase (1)

mTOR (1)

LDL (1)

NADPH (1)

Neurokinin receptor (1)

FGFR (1)

NF-κB (1)

Fatty Acid Synthase (1)

Nrf2 (1)

ERK (1)

Opioid Receptor (1)

Drug Metabolite (1)

Oxytocin Receptor (1)

P2X Receptor (1)

DNA Methyltransferase (1)

DHFR (1)

Xanthine Oxidase (1)

Library Information Sample

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty