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Anti-FBPase1 Antibody (6B758)
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Catalog No. TMAH-00421
Alias Fructose-1, FBPase 1, FBP1, FBP, D-Fructose-1, 6-Bisphosphate 1-Phosphohydrolase 1, 6-Bisphosphatase 1
Anti-FBPase1 Antibody (6B758) is an antibody targeting FBPase1. Anti-FBPase1 Antibody (6B758) can be used in ELISA, IHC.
Anti-FBPase1 Antibody (6B758)
Anti-FBPase1 Antibody (6B758)
😃Good
Catalog No. TMAH-00421Alias Fructose-1, FBPase 1, FBP1, FBP, D-Fructose-1, 6-Bisphosphate 1-Phosphohydrolase 1, 6-Bisphosphatase 1
Anti-FBPase1 Antibody (6B758) is an antibody targeting FBPase1. Anti-FBPase1 Antibody (6B758) can be used in ELISA, IHC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $207 | 7-10 days | |
| 100 μL | $348 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Recombinant Rabbit Monoclonal Application: ELISA, IHC Reactivity: Human |
| Alias | Fructose-1, FBPase 1, FBP1, FBP, D-Fructose-1, 6-Bisphosphate 1-Phosphohydrolase 1, 6-Bisphosphatase 1 |
| Ig Type | Rabbit IgG |
| Clone | 6B758 |
| Reactivity | Human |
| Verified Activity | IHC image of TMAH-00421 diluted at 1:100 and staining in paraffin-embedded human pancreatic tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
| Application | ELISA, IHC |
| Recommended Dose | IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human FBP1 |
| Antigen Species | Human |
| Gene ID | 2203 |
| Uniprot ID | |
| Biology Area | Epigenetics and Nuclear Signaling, Cancer, Metabolism, Signal transduction |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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