DSG3 Protein, Human, Recombinant (His)

Name: DSG3 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPK-00871
Price: 51 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: SG3, PVA, DSG-3, DSG3, Desmoglein-3, CDHF6) Copy Product Info

Synonyms: SG3, PVA, DSG-3, DSG3, Desmoglein-3, CDHF6

Catalog No. TMPK-00871 Copy Product Info

To identify genes that could potentially serve as molecular therapeutic markers for human head and neck cancer (HNC),DSG3 is identified overexpressed in HNC, with the degree of overexpression associated with clinicopathologic features of the tumor. Inhibition of DSG3 significantly suppresses carcinogenic potential in cellular and in vivo animal studies. DSG3 is a potential molecular target in the development of adjuvant therapy for HNC. DSG3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 64 kDa and the accession number is P32926.

Pack Size	Price	USA Stock	Global Stock
5 µg	$51	-	In Stock
10 µg	$80	-	In Stock
20 µg	$129	-	In Stock
50 µg	$248	-	In Stock
100 µg	$418	-	In Stock
200 µg	$757	7-10 days	7-10 days
500 µg	$1,670	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Batch Information

Select Batch

Purity:> 95% as determined by Bis-Tris PAGE > 90% as determined by HPLC

Appearance:Liquid

Color:Transparent

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized Human DSG3, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-DSG3 Antibody, hFc Tag with the EC50 2.1ng/ml determined by ELISA.
Description	To identify genes that could potentially serve as molecular therapeutic markers for human head and neck cancer (HNC),DSG3 is identified overexpressed in HNC, with the degree of overexpression associated with clinicopathologic features of the tumor. Inhibition of DSG3 significantly suppresses carcinogenic potential in cellular and in vivo animal studies. DSG3 is a potential molecular target in the development of adjuvant therapy for HNC. DSG3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 64 kDa and the accession number is P32926.
Species	Human
Expression System	HEK293 Cells
Tag	C-His
Accession Number	P32926
Construction	Glu50-Arg615
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	SG3, PVA, DSG-3, DSG3, Desmoglein-3, CDHF6
Research Background	To identify genes that could potentially serve as molecular therapeutic markers for human head and neck cancer (HNC),DSG3 is identified overexpressed in HNC, with the degree of overexpression associated with clinicopathologic features of the tumor. Inhibition of DSG3 significantly suppresses carcinogenic potential in cellular and in vivo animal studies. DSG3 is a potential molecular target in the development of adjuvant therapy for HNC.

Chemical Properties

Molecular Weight

64 kDa (predicted). Due to glycosylation, the protein migrates to 70-75 kDa based on Tris-Bis PAGE result.

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.