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Anti-ARL2BP Antibody (6K854) is a Rabbit antibody targeting ARL2BP. Anti-ARL2BP Antibody (6K854) can be used in ELISA,ICC/IF.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $268 | 7-10 days |
Description | Anti-ARL2BP Antibody (6K854) is a Rabbit antibody targeting ARL2BP. Anti-ARL2BP Antibody (6K854) can be used in ELISA,ICC/IF. |
Alias | RP66, BART1, BART, ADP-ribosylation factor-like 2 binding protein |
Ig Type | Monoclonal Rabbit IgG |
Clone | 6K854 |
Reactivity | Human |
Verified Activity | Immunofluorescence staining of ARL2BP in U2OS cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-human ARL2BP monoclonal antibody (1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green). |
Application | ELISA,ICC/IF |
Recommended Dose | ELISA: 1:5000-1:10000; ICC-IF: 1:20-1:100 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human ARL2BP / BART1 (rh ARL2BP / BART1; TMPY-03500; Q9Y2Y0-1; Met1-His163). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. ARL2BP binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of ARL2BP or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. ARL2BP is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity. ARL2BP, together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. ARL2BP may play a role as an effector of ARL2. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human ARL2BP / BART1 protein (TMPY-03500) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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