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Anti-ABCG8 Polyclonal Antibody
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Catalog No. TMAB-00026
Alias STSL, Sterolin 2, MGC142217, ATP binding cassette sub family G(WHITE) member 8(sterolin 2), ATP binding cassette sub family G member 8, ABCG8
Anti-ABCG8 Polyclonal Antibody is a Rabbit antibody targeting ABCG8. Anti-ABCG8 Polyclonal Antibody can be used in ELISA,IF,IHC-Fr,IHC-P,WB.
Anti-ABCG8 Polyclonal Antibody
Anti-ABCG8 Polyclonal Antibody
😃Good
Catalog No. TMAB-00026Alias STSL, Sterolin 2, MGC142217, ATP binding cassette sub family G(WHITE) member 8(sterolin 2), ATP binding cassette sub family G member 8, ABCG8
Anti-ABCG8 Polyclonal Antibody is a Rabbit antibody targeting ABCG8. Anti-ABCG8 Polyclonal Antibody can be used in ELISA,IF,IHC-Fr,IHC-P,WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $221 | 7-10 days | |
| 100 μL | $372 | 7-10 days | |
| 200 μL | $527 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-ABCG8 Polyclonal Antibody is a Rabbit antibody targeting ABCG8. Anti-ABCG8 Polyclonal Antibody can be used in ELISA,IF,IHC-Fr,IHC-P,WB. |
| Synonyms | STSL, Sterolin 2, MGC142217, ATP binding cassette sub family G(WHITE) member 8(sterolin 2), ATP binding cassette sub family G member 8, ABCG8 |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Multi-pass membrane protein (Probable). |
| Tissue Specificity | Strongly expressed in the liver, lower levels in the small intestine and colon. Detectable in a wide variety of human tissues. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008]. |
| Immunogen | KLH conjugated synthetic peptide: human ABCG8 |
| Antigen Species | Human |
| Gene Name | ABCG8 |
| Gene ID | |
| Protein Name | ATP-binding cassette sub-family G member 8 |
| Uniprot ID | |
| Biology Area | Metabolism of lipids and lipoproteins,Lipid transport,Cholesterol Metabolism,Cholesterol Metabolism,Lipid metabolism,Heart disease,Lipid metabolism |
| Function | Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile. |
| Molecular Weight | Theoretical: 76 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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