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BTS

Name: BTS
Brand: TargetMol
SKU: T7144
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T7144Cas No. 1576-37-0

Alias N-Tosylbenzylamine, N-Benzyl-p-toluenesulfonamide

BTS (N-Tosylbenzylamine) is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 : 5 μM) .

BTS

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Purity: 99.45%

Catalog No. T7144Alias N-Tosylbenzylamine, N-Benzyl-p-toluenesulfonamideCas No. 1576-37-0

BTS (N-Tosylbenzylamine) is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 : 5 μM) .

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 g	$29	-	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Purity:99.45%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	BTS (N-Tosylbenzylamine) is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 : 5 μM) .
Targets&IC50	Myosin S1 ATPase (Ca2+ stimulated):5 μM
In vivo	BTS is remarkably specific, as it was much less effective in suppressing contraction in rat myocardial or rabbit slow-twitch muscle, and did not inhibit platelet myosin II.?The isolation of BTS and the recently discovered Eg5 kinesin inhibitor, monastrol, suggests that motor proteins may be potential targets for therapeutic applications.
Synonyms	N-Tosylbenzylamine, N-Benzyl-p-toluenesulfonamide

Chemical Properties

Molecular Weight	261.34
Formula	C₁₄H₁₅NO₂S
Cas No.	1576-37-0
Smiles	CC1=CC=C(C=C1)S(=O)(=O)NCC1=CC=CC=C1
Relative Density.	1.204 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 75 mg/mL (286.98 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (7.65 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.8264 mL	19.1322 mL	38.2643 mL	191.3216 mL
5 mM	0.7653 mL	3.8264 mL	7.6529 mL	38.2643 mL
10 mM	0.3826 mL	1.9132 mL	3.8264 mL	19.1322 mL
20 mM	0.1913 mL	0.9566 mL	1.9132 mL	9.5661 mL
50 mM	0.0765 mL	0.3826 mL	0.7653 mL	3.8264 mL
100 mM	0.0383 mL	0.1913 mL	0.3826 mL	1.9132 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc